Tofacitinib as treatment for nail lichen planus associated with alopecia universalis

M Iorizzo, E Haneke - JAMA dermatology, 2021 - jamanetwork.com
Discussion Lichen planus is a benign inflammatory disorder of unknown etiology that may
affect the skin, mucosae, scalp, and nails. Few medications with proven efficacy exist, and …

Emerging medical treatments for hidradenitis suppurativa

AB Lyons, N Shabeeb, CL Nicholson… - Journal of the American …, 2020 - Elsevier
Hidradenitis suppurativa (HS) is a chronic inflammatory disease affecting intertriginous skin
areas, and it is characterized by recurrent painful episodes of inflammatory drainage …

Evaluating topical JAK inhibitors as a treatment option for atopic dermatitis

MI Fardos, R Singh, PO Perche, KA Kelly… - Expert Review of …, 2022 - Taylor & Francis
Introduction Atopic dermatitis (AD) is a chronic, inflammatory skin condition mediated by
cytokines that utilize the Janus Kinase/Signal Transducer and Activator of Transcription (JAK …

Skin cancers under Janus kinase inhibitors: a World Health Organization drug safety database analysis

C Jalles, M Lepelley, S Mouret, J Charles, MT Leccia… - Therapies, 2022 - Elsevier
Background Janus kinase (JAK) inhibitors are targeted therapies with a potential
imunomodulatory and anti-inflammatory effect, indicated in various dysimmune pathologies …

Emerging drugs for alopecia areata: JAK inhibitors

M Iorizzo, A Tosti - Expert opinion on emerging drugs, 2018 - Taylor & Francis
ABSTRACT Introduction: Alopecia Areata is a common form of non-scarring hair loss that
usually starts abruptly with a very high psychological impact. Due to the still not completely …

JAK3-selective inhibitor peficitinib for the treatment of rheumatoid arthritis

Q Qiu, Q Feng, X Tan, M Guo - Expert Review of Clinical …, 2019 - Taylor & Francis
Introduction: Rheumatoid arthritis (RA) is a chronic progressive autoimmune disease
characterized by synovitis as well as symmetric and destructive arthropathy. Although …

Dysregulation of inflammatory gene expression in lesional and nonlesional skin of patients with pyoderma gangrenosum

AG Ortega‐Loayza, WH Nugent… - British Journal of …, 2018 - academic.oup.com
DEAR EDITOR, Pyoderma gangrenosum (PG) is an inflammatory skin condition that often
presents as chronic ulcers. It is often idiopathic but can be associated with systemic …

Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex, and disease severity

M Ragab, E Hassan, D Niely… - Advances in Dermatology …, 2020 - termedia.pl
Serum level of interleukin-15 in active alopecia areata patients and its relation to age, sex,
and disease severity Page 1 Advances in Dermatology and Allergology 6, December/2020 …

A case of topical ruxolitinib treatment failure in alopecia areata

M Deeb, RA Beach - Journal of Cutaneous Medicine and …, 2017 - journals.sagepub.com
Alopecia areata (AA) is an autoimmune-mediated, nonscarring form of hair loss. Despite its
prevalence, current management options are limited, especially when the disease has …

Topical tofacitinib for patients with lichen planopilaris and/or frontal fibrosing alopecia

LC Chen, C Ogbutor, KJ Kelley, MM Senna - Journal of the American …, 2024 - Elsevier
Lichen planopilaris (LPP) is a primary lymphocytic cicatricial alopecia characterized by stem
44 cell destruction in hair follicle bulge. 1 Frontal fibrosing alopecia (FFA) is a clinical variant …