International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia

GF Watts, SS Gidding, RA Hegele, FJ Raal… - Nature Reviews …, 2023 - nature.com
This contemporary, international, evidence-informed guidance aims to achieve the greatest
good for the greatest number of people with familial hypercholesterolaemia (FH) across …

[HTML][HTML] Recent advances in the management and implementation of care for familial hypercholesterolaemia

NSR Lan, A Bajaj, GF Watts, M Cuchel - Pharmacological research, 2023 - Elsevier
Familial hypercholesterolaemia (FH) is a common autosomal semi-dominant and highly
penetrant disorder of the low-density lipoprotein (LDL) receptor pathway, characterised by …

Lipid distributions in the Global Diagnostics Network across five continents

SS Martin, JK Niles, HW Kaufman, Z Awan… - European heart …, 2023 - academic.oup.com
Aims Lipids are central in the development of cardiovascular disease, and the present study
aimed to characterize variation in lipid profiles across different countries to improve …

[HTML][HTML] Accuracy of 23 equations for estimating LDL cholesterol in a clinical laboratory database of 5,051,467 patients

C Samuel, J Park, A Sajja, ED Michos… - Global Heart, 2023 - ncbi.nlm.nih.gov
Background: Alternatives to the Friedewald low-density lipoprotein cholesterol (LDL-C)
equation have been proposed. Objective: To compare the accuracy of available LDL-C …

[HTML][HTML] World Heart Federation roadmap for secondary prevention of cardiovascular disease: 2023 update

L Laranjo, F Lanas, MC Sun, DA Chen, L Hynes… - Global …, 2024 - ncbi.nlm.nih.gov
Background: Secondary prevention lifestyle and pharmacological treatment of
atherosclerotic cardiovascular disease (ASCVD) reduce a high proportion of recurrent …

[HTML][HTML] Cardiovascular Disease in Saudi Arabia: Facts and the way forward

AA Tash, RF Al-Bawardy - Journal of the Saudi Heart Association, 2023 - ncbi.nlm.nih.gov
Cardiovascular diseases (CVDs) remain a major health concern globally. While some risk
factors for CVDs are non-modifiable, other determinants like obesity, hypertension, type-2 …

Future directions in psychiatric neurosurgery: proceedings of the 2022 American Society for Stereotactic and Functional Neurosurgery meeting on surgical …

FL Hitti, AS Widge, P Riva-Posse, DA Malone Jr… - Brain Stimulation, 2023 - Elsevier
Objective. Despite advances in the treatment of psychiatric diseases, currently available
therapies do not provide sufficient and durable relief for as many as 30–40% of patients …

Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study

KI Dharmayat, AJ Vallejo-Vaz, CAT Stevens… - The Lancet, 2024 - thelancet.com
Background Approximately 450 000 children are born with familial hypercholesterolaemia
worldwide every year, yet only 2· 1% of adults with familial hypercholesterolaemia were …

Optimizing cardiovascular disease risk screening in a low-resource setting: cost-effectiveness of program modifications in Sri Lanka modelled with nationally …

N Wijemunige, RP Rannan-Eliya, P Van Baal… - BMC Public Health, 2023 - Springer
Background While screening for cardiovascular disease (CVD) risk can help low-resource
health systems deliver low-cost, effective prevention, evidence is needed to adapt …

The LDL cumulative exposure hypothesis: evidence and practical applications

BA Ference, E Braunwald, AL Catapano - Nature Reviews Cardiology, 2024 - nature.com
The trapping of LDL and other apolipoprotein B-containing lipoproteins within the artery wall
causes atherosclerosis. As more LDL becomes trapped within the artery wall over time, the …