[HTML][HTML] Global pandemics interconnected—obesity, impaired metabolic health and COVID-19

N Stefan, AL Birkenfeld, MB Schulze - Nature Reviews Endocrinology, 2021 - nature.com
Obesity and impaired metabolic health are established risk factors for the non-
communicable diseases (NCDs) type 2 diabetes mellitus, cardiovascular disease …

Immune system and COVID-19 by sex differences and age

T Ciarambino, O Para, M Giordano - Women's Health, 2021 - journals.sagepub.com
In COVID-19 disease, are reported gender differences in relation to severity and death. The
aim of this review is to highlight gender differences in the immune response to COVID-19 …

Chronic respiratory diseases are predictors of severe outcome in COVID-19 hospitalised patients: a nationwide study

G Beltramo, J Cottenet, AS Mariet… - European …, 2021 - Eur Respiratory Soc
Background Influenza epidemics were initially considered to be a suitable model for the
COVID-19 epidemic, but there is a lack of data concerning patients with chronic respiratory …

Role of neutrophils in acute viral infection

Y Ma, Y Zhang, L Zhu - Immunity, inflammation and disease, 2021 - Wiley Online Library
Neutrophils play multiple roles in acute viral infections. They restrict viral replication and
diffusion through phagocytosis, degranulation, respiratory burst, secretion of cytokines, and …

Understanding NK cell biology for harnessing NK cell therapies: targeting cancer and beyond

E Shin, SH Bak, T Park, JW Kim, SR Yoon… - Frontiers in …, 2023 - frontiersin.org
Gene-engineered immune cell therapies have partially transformed cancer treatment, as
exemplified by the use of chimeric antigen receptor (CAR)-T cells in certain hematologic …

How immunosenescence and inflammaging may contribute to hyperinflammatory syndrome in COVID-19

L Müller, S Di Benedetto - International journal of molecular sciences, 2021 - mdpi.com
Aging is characterized by the dynamic remodeling of the immune system designated
“immunosenescence,” and is associated with altered hematopoiesis, thymic involution, and …

Genetic mechanisms of COVID-19 and its association with smoking and alcohol consumption

S Rao, A Baranova, H Cao, J Chen… - Briefings in …, 2021 - academic.oup.com
We aimed to investigate the genetic mechanisms associated with coronavirus disease of
2019 (COVID-19) outcomes in the host and to evaluate the possible associations between …

[HTML][HTML] Exploiting the molecular basis of age and gender differences in outcomes of SARS-CoV-2 infections

D Mercatelli, E Pedace, P Veltri, FM Giorgi… - Computational and …, 2021 - Elsevier
Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection
(coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It …

Aged brain and neuroimmune responses to COVID-19: post-acute sequelae and modulatory effects of behavioral and nutritional interventions

L Müller, S Di Benedetto - Immunity & Ageing, 2023 - Springer
Advanced age is one of the significant risk determinants for coronavirus disease 2019
(COVID-19)-related mortality and for long COVID complications. The contributing factors …

Thymic aging may be associated with COVID-19 pathophysiology in the elderly

W Wang, R Thomas, J Oh, DM Su - Cells, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused the global
pandemic of coronavirus disease 2019 (COVID-19) and particularly exhibits severe …