Bacillus anthracis, the anthrax agent, is a member of the Bacillus cereus sensu lato group,
which includes invasive pathogens of mammals or insects as well as nonpathogenic …

Iron is an essential nutrient for many bacteria. Since the metal is highly sequestered in host
tissues, bound predominantly to heme, pathogenic bacteria often take advantage of heme …

Heme proteins are extremely diverse, widespread, and versatile biocatalysts, sensors, and
molecular transporters. The chlorite dismutase family of hemoproteins received its name due …

The acquisition and metabolism of iron (Fe) by the human pathogen S taphylococcus aureus
is critical for disease progression. S. aureus requires Fe to synthesize inorganic cofactors …

IsdB is a receptor on the surface of the bacterial pathogen Staphylococcus aureus that
extracts heme from hemoglobin (Hb) to enable growth on Hb as a sole iron source. IsdB is …

Recent progress in genetics, fed by the burst in genome sequence data, has led to the
identification of a host of novel bacterial heme proteins that are now being characterized in …

ABSTRACT The protein YfeX from Escherichia coli has been proposed to be essential for
the process of iron removal from heme by carrying out a dechelation of heme without …

The element iron is essential for bacteria and plays a key role in the virulence and pathology
of bacterial diseases. The largest reservoir of iron within the human body is in …

For decades it has been known that an out-of-plane ruffling distortion of heme perturbs its
UV–vis absorption (Abs) spectrum, but whether increased ruffling induces a red or blue shift …

IsdI, a heme-degrading protein from Staphylococcus aureus, binds heme in a manner that
distorts the normally planar heme prosthetic group to an extent greater than that observed so …