[HTML][HTML] Emerging Role of Environmental Epitranscriptomics and RNA Modifications in Parkinson's Disease
JT Gionco, AI Bernstein - Journal of Parkinson's disease, 2024 - content.iospress.com
Environmental risk factors and gene-environment interactions play a critical role in
Parkinson's disease (PD). However, the relatively large contribution of environmental risk …
Parkinson's disease (PD). However, the relatively large contribution of environmental risk …
[HTML][HTML] Regulatory role of m6A epitranscriptomic modifications in normal development and congenital malformations during embryogenesis
Y Yao, P Liu, Y Li, W Wang, H Jia, Y Bai, Z Yuan… - Biomedicine & …, 2024 - Elsevier
The discovery of N6-methyladenosine (m 6 A) methylation and its role in translation has led
to the emergence of a new field of research. Despite accumulating evidence suggesting that …
to the emergence of a new field of research. Despite accumulating evidence suggesting that …
N6-methyladenosine promotes aberrant redox homeostasis required for arsenic carcinogenesis by controlling the adaptation of key antioxidant enzymes
T Zhao, D Sun, K Long, W Xiong, J Man… - Journal of Hazardous …, 2024 - Elsevier
Abstract N 6-methyladenosine (m 6 A), a high-profile RNA epigenetic modification, responds
to oxidative stress and temporal-specifically mediates arsenic carcinogenesis. However …
to oxidative stress and temporal-specifically mediates arsenic carcinogenesis. However …
[HTML][HTML] Manganese induces podocyte injury through regulating MTDH/ALKBH5/NLRP10 axis: Combined analysis at epidemiology and molecular biology levels
Q Liang, J Jing, H He, X Huang, J Liu, M Wang… - Environment …, 2024 - Elsevier
Manganese (Mn) is an essential micronutrient required for various biological processes but
excess exposure to Mn can cause neurotoxicity. However, there are few reports regarding …
excess exposure to Mn can cause neurotoxicity. However, there are few reports regarding …
Targeting m6A mRNA demethylase FTO alleviates manganese-induced cognitive memory deficits in mice
Y Wen, Z Fu, J Li, M Liu, X Wang, J Chen… - Journal of Hazardous …, 2024 - Elsevier
Manganese (Mn) induced learning and memory deficits through mechanisms that are not
fully understood. In this study, we discovered that the demethylase FTO was significantly …
fully understood. In this study, we discovered that the demethylase FTO was significantly …
[HTML][HTML] IGF2BP3-mediated regulation of GLS and GLUD1 gene expression promotes treg-induced immune escape in human cervical cancer
T Zhou, Z Xiao, J Lu, L Zhang, L Bo… - American Journal of …, 2023 - ncbi.nlm.nih.gov
This study aimed to investigate the impact of IGF2BP3, a well-known m6A modification-
related protein, on the metabolic and immune microenvironment of human cervical cancer …
related protein, on the metabolic and immune microenvironment of human cervical cancer …
[HTML][HTML] Effects and mechanisms of N6-methyladenosine RNA methylation in environmental pollutant-induced carcinogenesis
T Li, Z Xu, K Zhang, X Yang, A Thakur, S Zeng… - Ecotoxicology and …, 2024 - Elsevier
Environmental pollution, including air pollution, plastic contamination, and heavy metal
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …
exposure, is a pressing global issue. This crisis contributes significantly to pollution-related …
Epigenetics and environmental health
M Zhang, T Hu, T Ma, W Huang, Y Wang - Frontiers of Medicine, 2024 - Springer
Epigenetic modifications including DNA methylation, histone modifications, chromatin
remodeling, and RNA modifications complicate gene regulation and heredity and profoundly …
remodeling, and RNA modifications complicate gene regulation and heredity and profoundly …