The ATP-binding cassette superfamily member ABCB5 identifies a subset of skin-resident
mesenchymal stem cells (MSCs) that exhibit potent immunomodulatory and wound healing …

More than 10% of the world's population suffers from osteoarthritis (OA) of the knee, with a
lifetime risk of 45%. Current treatments for knee OA pain are as follows: weight control; oral …

Human adipose tissue-derived stem/stromal cells (hASCs) are adult multipotent
mesenchymal stem/stromal cells with immunomodulatory capacities. Here, we present up-to …

Spinocerebellar ataxias are heritable neurodegenerative diseases caused by a cytosine-
adenine-guanine expansion, which encodes a long glutamine tract (polyglutamine) in the …

Simple Summary Horses are high-level athletic athletes prone to musculoskeletal injuries.
Tendon/ligament injuries are the most frequent types of injuries which that are very difficult to …

Obesity is a highly prevalent condition often associated with dysfunctional adipose tissue.
Stem cell-based therapies have become a promising tool for therapeutic intervention in the …

Mismatches between pre-clinical and clinical results of stem cell therapeutics for ischemic
stroke limit their clinical applicability. To overcome these discrepancies, precise planning of …

Cell-based therapeutics are promising interventions to repair ischemic cardiac tissue.
However, no single cell type has yet been found to be both specialized and versatile enough …

Mesenchymal stem cells (MSCs) are being increasingly used in various therapeutic
applications including skin tissue repair and wound healing. The positive effects of the …

Diabetes mellitus contributes to 15–25% of all chronic foot ulcers. Peripheral vascular
disease is a cause of ischemic ulcers and exacerbates diabetic foot disease. Cell-based …