The benefits of autologous cell therapy for cardiac repair are diminished in aged individuals
due to the limited quality and poor tolerance of aged stem cells in the ischemic micro …

Objective Several clinical trials aimed at treating various autoimmune diseases, including
systemic lupus erythematosus (SLE), by introducing mesenchymal stem cells (MSCs) have …

The musculoskeletal system, which is vital for movement, support, and protection, can be
impaired by disorders such as osteoporosis, osteoarthritis, and muscular dystrophy. This …

Adipose-derived stem cells comprise several clinically beneficial qualities that have been
explored in basic research and have motivated several clinical studies with promising …

Mesenchymal stromal cells have been the subject of an expanding number of studies over
the past decades. Today, over 75,000 publications are available that shine light on the …

Osteoarthritis is a multifactorial disease characterized by cartilage degeneration, while
cartilage progenitor/stem cells (CPCs) are responsible for endogenous cartilage repair …

Promising preclinical stroke research has not yielded meaningful and significant success in
clinical trials. This lack of success has prompted the need for refinement of preclinical …

For many years optimal treatment for dysfunctional skeletal muscle characterized, for
example, by impaired or limited regeneration, has been searched. Among the crucial factors …

Introduction Heart valve disease is a growing burden on the healthcare system. Current
solutions are insufficient for young patients and do not offer relief from reintervention. Tissue …

Progress in synthetic biology has enabled the construction of designer cells that sense
biological inputs, and, in response, activate user-defined biomolecular programs. Such …