Mesenchymal stem/stromal cells in progressive fibrogenic involvement and anti-fibrosis therapeutic properties

C Li, B Wang - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
Fibrosis refers to the connective tissue deposition and stiffness usually as a result of injury.
Fibrosis tissue-resident mesenchymal cells, including fibroblasts, myofibroblast, smooth …

Human-Induced Pluripotent Stem Cells in Plastic and Reconstructive Surgery

N Hadzimustafic, A D'Elia, V Shamoun… - International Journal of …, 2024 - mdpi.com
A hallmark of plastic and reconstructive surgery is restoring form and function. Historically,
tissue procured from healthy portions of a patient's body has been used to fill defects, but …

Current Advances in Mesenchymal Stem Cell Therapies Applied to Wounds and Skin, Eye, and Neuromuscular Diseases in Companion Animals

RA Picazo, C Rojo, J Rodriguez-Quiros… - Animals, 2024 - mdpi.com
Simple Summary The search for alternative treatments is necessary for diseases where
conventional therapies are ineffective. In recent years, therapies using mesenchymal stem …

Nasal mucosa-derived mesenchymal stem cells prolonged the survival of septic rats by protecting macrophages from pyroptosis

L Zhang, Z Wang, X Sun, W Rong, W Deng, J Yu… - Cellular …, 2024 - Elsevier
Sepsis is characterized by an exacerbated inflammatory response, driven by the
overproduction of cytokines, a phenomenon known as a cytokine storm. This condition is …

[HTML][HTML] Dual production of human mesenchymal stromal cells and derived extracellular vesicles in a dissolvable microcarrier-based stirred culture system

H Bandarra-Tavares, T Franchi-Mendes, C Ulpiano… - Cytotherapy, 2024 - Elsevier
Background & aims Cell therapies based on mesenchymal stromal cells (MSCs) have
gained an increasing therapeutic interest in the context of multiple disorders. Nonetheless …

Cellular therapies for bone repair: current insights

P Rodham, F Khaliq, V Giannoudis… - Journal of Orthopaedics …, 2024 - Springer
Mesenchymal stem cells are core to bone homeostasis and repair. They both provide the
progenitor cells from which bone cells are formed and regulate the local cytokine …

Immunogenicity of mesenchymal stromal/stem cells

W Chen, L Lv, N Chen, E Cui - Scandinavian Journal of …, 2023 - Wiley Online Library
Mesenchymal stromal/stem cells (MSCs) possess the ability to self‐renew and differentiate
into other cell types. Because of their anti‐inflammatory and immunomodulatory abilities, as …

Automated Production at Scale of Induced Pluripotent Stem Cell-Derived Mesenchymal Stromal Cells, Chondrocytes and Extracellular Vehicles: Towards Real-Time …

L Herbst, F Groten, M Murphy, G Shaw, B Nießing… - Processes, 2023 - mdpi.com
Induced pluripotent stem cell (iPSC)-derived mesenchymal stem cells (iMSCs) are
amenable for use in a clinical setting for treatment of osteoarthritis (OA), which remains one …

Freeze‐Dried Mesenchymal Stem Cells: From Bench to Bedside. Review

T Paresishvili, Z Kakabadze - Advanced Biology, 2024 - Wiley Online Library
This review describes the freeze‐dried mesenchymal stem cells (MSCs) and their ability to
restore damaged tissues and organs. An analysis of the literature shows that after the …

[HTML][HTML] Controversies regarding transplantation of mesenchymal stem cells

T Velikova, T Dekova, DG Miteva - World Journal of Transplantation, 2024 - wjgnet.com
Mesenchymal stem cells (MSCs) have tantalized regenerative medicine with their
therapeutic potential, yet a cloud of controversies looms over their clinical tran splantation …