Human MCF-7 breast cancer cells were exposed to a Random Positioning Machine (RPM).
After 24 hours (h) the cells grew either adherently within a monolayer (AD) or within …

Tissue engineering of chondrocytes on a Random Positioning Machine (RPM) is a new
strategy for cartilage regeneration. Using a three-dimensional RPM, a device designed to …

Abstract Space environment provides many challenges to pilots, astronauts, and space
scientists, which are constantly subjected to unique conditions, including microgravity …

Background Multicellular tumor spheroids (MCTS) formed scaffold-free under microgravity
are of high interest for research and medicine. Their formation mechanism can be studied in …

Real and simulated microgravity induce a variety of changes in human cells. Most
importantly, changes in the cytoskeleton have been noted, and studies on microtubules …

This study focused on the effects of short‐term microgravity (22 s) on the gene expression
and morphology of endothelial cells (ECs) and evaluated gravisensitive signaling elements …

What makes microgravity an interesting and unique tool for gerontologists is that many
space-related physiological changes resemble those observed during ageing, but are more …

A migration of cancer is one of the most important factors affecting cancer therapy.
Particularly, a cancer migration study in a microgravity environment has gained attention as …

Prostate cancer is one of the leading causes of cancer mortality in men worldwide. An
unusual but unique environment for studying tumor cell processes is provided by …

Health hazards in astronauts are represented by cardiovascular problems and impaired
bone healing. These disturbances are characterized by a common event, the loss of function …