Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

Biological and functional multimorbidity—from mechanisms to management

C Langenberg, AD Hingorani, CJM Whitty - Nature Medicine, 2023 - nature.com
Globally, the number of people with multiple co-occurring diseases will increase
substantially over the coming decades, with important consequences for patients, carers …

COPD and multimorbidity: recognising and addressing a syndemic occurrence

LM Fabbri, BR Celli, A Agustí, GJ Criner… - The Lancet …, 2023 - thelancet.com
Most patients with chronic obstructive pulmonary disease (COPD) have at least one
additional, clinically relevant chronic disease. Those with the most severe airflow obstruction …

Pragmatic Trial of Hospitalization Rate in Chronic Kidney Disease

MA Vazquez, G Oliver, R Amarasingham… - … England Journal of …, 2024 - Mass Medical Soc
Background Despite the availability of effective therapies for patients with chronic kidney
disease, type 2 diabetes, and hypertension (the kidney-dysfunction triad), the results of large …

Healthcare fragmentation, multimorbidity, potentially inappropriate medication, and mortality: a Danish nationwide cohort study

A Prior, CH Vestergaard, P Vedsted, SM Smith… - BMC medicine, 2023 - Springer
Background Patients with multimorbidity are frequent users of healthcare, but fragmented
care may lead to suboptimal treatment. Yet, this has never been examined across …

Aging-related comorbidity burden among women and men with or at-risk for HIV in the US, 2008-2019

LF Collins, FJ Palella, CC Mehta… - JAMA network …, 2023 - jamanetwork.com
Importance Despite aging-related comorbidities representing a growing threat to quality-of-
life and mortality among persons with HIV (PWH), clinical guidance for comorbidity …

Understanding primary care transformation and implications for ageing populations and health inequalities: a systematic scoping review of new models of primary …

DAG Henderson, E Donaghy, M Dozier, B Guthrie… - BMC medicine, 2023 - Springer
Background Many countries have introduced reforms with the aim of primary care
transformation (PCT). Common objectives include meeting service delivery challenges …

Etiology, effects and management of comorbidities in multiple sclerosis: recent advances

RA Marrie, JD Fisk, K Fitzgerald, K Kowalec… - Frontiers in …, 2023 - frontiersin.org
Comorbid conditions commonly affect people with multiple sclerosis (MS). Population-based
studies indicate that people with MS have an increased incidence of ischemic heart disease …

[HTML][HTML] Association between household air pollution from solid fuel use and risk of chronic diseases and their multimorbidity among Chinese adults

W Shi, T Zhang, Y Li, Y Huang, L Luo - Environment International, 2022 - Elsevier
Background Given the increasing burden of chronic conditions, multimorbidity is now a
priority for public health systems worldwide. However, the relationship between household …

The trajectory of very old critically ill patients

B Guidet, H Vallet, H Flaatten, G Joynt… - Intensive Care …, 2024 - Springer
The demographic shift, together with financial constraint, justify a re-evaluation of the
trajectory of care of very old critically ill patients (VIP), defined as older than 80 years. We …