Omega-3 fatty acids abrogates oxido-inflammatory and mitochondrial dysfunction-associated apoptotic responses in testis of tamoxifen-treated rats

AF Odetayo, RE Akhigbe, MA Hamed… - Frontiers in …, 2024 - frontiersin.org
Background Tamoxifen (TAM) is a widely used drug in patients with gynecomastia and
breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately …

L-Arginine abrogates maternal and pre-pubertal codeine exposure-induced impaired spermatogenesis and sperm quality by modulating the levels of mRNA encoding …

RE Akhigbe, OA Afolabi, AF Ajayi - Frontiers in Endocrinology, 2023 - frontiersin.org
Introduction Although, codeine has been demonstrated to lower sperm quality; the effects of
maternal and prepubertal codeine exposure on male offspring is yet to be reported. In …

Co-administration of HAART and antikoch triggers cardiometabolic dysfunction through an oxidative stress-mediated pathway

RE Akhigbe, MA Hamed - Lipids in Health and Disease, 2021 - Springer
Background Antikoch and highly active anti-retroviral therapy are effective drugs in the
management of tuberculosis and Human Immunodeficiency Virus, respectively. However …

L-Arginine reverses maternal and pre-pubertal codeine exposure-induced sexual dysfunction via upregulation of androgen receptor gene and NO/cGMP signaling

RE Akhigbe, OA Afolabi, AF Ajayi - Plos one, 2022 - journals.plos.org
Background Although codeine has been reported to enhance sexual activity by improving
penile reflexes, it has been shown to impair fertility indices. Also, codeine impairs ovarian …

Histomorphometric changes in testis following administration of tenofovir nanoparticles in an animal model

EC Naidu, SO Olojede, SK Lawal, OO Azu - Discover Nano, 2024 - Springer
Background Nanoparticle-based drugs are new inventions in the management of the
Human immunodeficiency virus (HIV) pandemic, especially resistant forms of the virus in …

Androgen Receptor (AR) Depletion Underlies the Reproductive Dysfunctions in Male Rats Exposed to Alcohol and Combination Antiretroviral Therapy (cART)

E Owembabazi, P Nkomozepi, EF Mbajiorgu - Andrologia, 2023 - Wiley Online Library
The prevalence of alcohol abuse and HIV/AIDS is high in males of reproductive age;
unfortunately, a high incidence of alcohol intake has been reported in HIV/AIDS patients …

Selenium and Omega-3 Fatty Acids Ameliorate Highly Active Anti-Retroviral Therapy (HAART)-induced Reproductive Impairment in Male Wistar Rats

E Aribo, NE Udokang, VE Sunday… - Nigerian Journal of …, 2023 - ojshostng.com
Highly active anti-retroviral therapy (HAART) is currently the main stay in the treatment of
Human Immunodeficiency Virus (HIV) disease. This treatment regimen typically combines …

[PDF][PDF] Research Article Androgen Receptor (AR) Depletion Underlies the Reproductive Dysfunctions in Male Rats Exposed to Alcohol and Combination Antiretroviral …

E Owembabazi, P Nkomozepi, EF Mbajiorgu - 2023 - academia.edu
The prevalence of alcohol abuse and HIV/AIDS is high in males of reproductive age;
unfortunately, a high incidence of alcohol intake has been reported in HIV/AIDS patients …

[PDF][PDF] The Supreme Court of Appeal Limits the Deduction of Expenditure Incurred in the Production of the Income The Commissioner for the South African Revenue …

T Legwaila - 2023 - wiredspace.wits.ac.za
The prevalence of alcohol abuse and HIV/AIDS is high in males of reproductive age;
unfortunately, a high incidence of alcohol intake has been reported in HIV/AIDS patients …