[HTML][HTML] The role of RAGE in host pathology and crosstalk between RAGE and TLR4 in innate immune signal transduction pathways

D Prantner, S Nallar, SN Vogel - FASEB journal: official publication …, 2020 - ncbi.nlm.nih.gov
Although the innate immune receptor protein, Receptor for Advanced Glycation End
products (RAGE), has been extensively studied, there has been renewed interest in RAGE …

Propolis: A useful agent on psychiatric and neurological disorders? A focus on CAPE and pinocembrin components

CCS Menezes da Silveira, DA Luz… - Medicinal research …, 2021 - Wiley Online Library
Propolis consists of a honeybee product, with a complex mix of substances that have been
widely used in traditional medicine. Among several compounds present in propolis, caffeic …

[HTML][HTML] Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

A Pecorelli, V Cordone, N Messano, C Zhang, S Falone… - Redox Biology, 2020 - Elsevier
Rett syndrome (RTT) is a progressive neurodevelopmental disorder mainly caused by
mutations in the X-linked MECP2 gene. RTT patients show multisystem disturbances …

The constitutive activation of TLR4-IRAK1-NFκB axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome …

V Cordone, F Ferrara, A Pecorelli, A Guiotto… - Free Radical Biology …, 2022 - Elsevier
Rett syndrome (RTT), a devastating neurodevelopmental disorder, is caused in 95% of the
cases by mutations in the X-chromosome-localized MECP2 gene. To date, RTT is …

[HTML][HTML] Molecular Assessment of Methylglyoxal-Induced Toxicity and Therapeutic Approaches in Various Diseases: Exploring the Interplay with the Glyoxalase …

M Alhujaily - Life, 2024 - mdpi.com
This comprehensive exploration delves into the intricate interplay of methylglyoxal (MG) and
glyoxalase 1 (GLO I) in various physiological and pathological contexts. The linchpin of the …

A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome

V Cicaloni, A Pecorelli, V Cordone, L Tinti… - Archives of Biochemistry …, 2020 - Elsevier
Rett syndrome (RTT) is a progressive neurodevelopmental disorder caused by mutations in
the X-linked MECP2 gene. RTT patients show multisystem disturbances associated with …

Circadian clock and oxinflammation: functional crosstalk in cutaneous homeostasis

E Frigato, M Benedusi, A Guiotto… - Oxidative Medicine …, 2020 - Wiley Online Library
Circadian rhythms are biological oscillations that occur with an approximately 24 h period
and optimize cellular homeostasis and responses to environmental stimuli. A growing …

The complexity of Rett syndrome models: Primary fibroblasts as a disease-in-a-dish reliable approach

V Cordone, A Pecorelli, F Amicarelli, J Hayek… - Drug Discovery Today …, 2020 - Elsevier
Rett syndrome (RTT) is a progressive neurodevelopmental disease, which affects almost
exclusively the female gender (prevalence of about 1: 10,000). RTT symptoms are usually …