Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania
POL Moreira, PM Nogueira, RL Monte-Neto - Microorganisms, 2023 - mdpi.com
Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still
lacking a safe and effective vaccine for humans. Given this scenario, the search for a new …
lacking a safe and effective vaccine for humans. Given this scenario, the search for a new …
Leishmania mexicana centrin knockout parasites promote M1-polarizing metabolic changes
G Volpedo, T Pacheco-Fernandez, T Oljuskin… - Iscience, 2023 - cell.com
Leishmaniasis is a tropical disease prevalent in 90 countries. Presently, there is no
approved vaccine for human use. We developed a live attenuated L. mexicana …
approved vaccine for human use. We developed a live attenuated L. mexicana …
Next-Generation Next-Generation Leishmanization: Revisiting Molecular Targets for Selecting Genetically Engineered Live-Attenuated Leishmania.
POL Moreira, PM Nogueira, RL Monte-Neto - 2023 - arca.fiocruz.br
CRISPR/Cas; genetic manipulation; leishmanization; live-attenuated Leishmania; vaccine.
Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still …
Despite decades of research devoted to finding a vaccine against leishmaniasis, we are still …