Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer as the
absence of cell surface receptors renders it more difficult to be therapeutically targeted …

CXCL1, a functional murine orthologue of the human chemokine CXCL8 (IL-8), and its
CXCR1 and CXCR2 receptors were investigated in a murine model of acquired epilepsy …

Background Cervical cancer as one of the most common malignant tumors lead to bad
prognosis among women. Some researches already focus on the carcinogenesis and …

Breast cancer is the most frequent cancer and the second leading cause of death among
women. Triple-negative breast cancer is the most aggressive subtype of breast cancer and …

The CXC motif chemokine receptor-1 (CXCR1) is a rhodopsin-like G-protein-coupled
receptor, expressed on the cell surface of immune cells and tumors. CXCR1 interacts with …

Chemotherapy-induced peripheral neuropathy (CIPN) is a type of neuropathic pain that
represents a frequent and serious consequence of chemotherapy agents. Over the last …

Therapeutic resistance is the major contributor to the poor prognosis of and low survival from
pancreatic cancer (PC). Cancer progression is a complex process reliant on interactions …

Abstract Interleukin-8 (IL-8/CXCL8) mediates its biological effects through two receptors,
CXCR1 and CXCR2. While CXCR1 recognizes IL-8 and granulocyte chemotactic protein-2 …

Breast cancer, a death-dealing disease mainly affects the women populace in the world.
Outmoded remedial treatments like chemo and radiotherapy against breast cancer have …

Abstract Interactions between interleukin (IL)-8 and its receptors, C‑XC chemokine receptor
1,(CXCR1) and CXCR2 serve crucial roles in increasing cancer progression. Inhibition of …