LAG-3 分子与免疫调节

田晓玲, 仇超, 徐建青 - 中华微生物学和免疫学杂志, 2013 - cqvip.com
淋巴细胞活化基因-3 (1ymphocyte activation gene 3, LAG. 3) 表达在活化的T 淋巴细胞, B
淋巴细胞, 自然杀伤细胞(natural killer cell, NK) 和浆细胞样树突状细胞(plasmacytoid dendritic …

ThymicPeptides Reverse Immune Exhaustion in Patients with Reactivated Human Alphaherpesvirus1 Infections

A Hymos, E Grywalska, J Klatka, M Klatka… - International Journal of …, 2020 - mdpi.com
Recurrent infection with human alphaherpesvirus 1 (HHV-1) may be associated with
immune exhaustion that impairs virus elimination. Thymic peptides enhance immune …

Human immunodeficiency virus type 1 Nef in human monocyte‐like cell line THP‐1 expands treg cells via toll‐like receptor 2

X Qin, J Yao, F Yang, J Nie, Y Wang… - Journal of Cellular …, 2011 - Wiley Online Library
Abstract CD4+ CD25+ regulatory T cells (Tregs) represent a unique T‐cell lineage that is
endowed with the ability to actively suppress immune responses in order to inhibit …

HIV-1 Exploitation of Dendritic Cell Functionality and Initial Responses in Mucosal Tissues: Elucidation of Influence of HIV-1 Complement Opsonization, and HIV-1 …

C Svanberg - 2023 - diva-portal.org
ABSTRACT Human immunodeficiency virus (HIV)-1 is transmitted between individuals via
sexual intercourse or via blood products. To date there are 38 million people living with …

Experimental exposure of Burkholderia pseudomallei crude culture filtrate upregulates PD-1 on T lymphocytes

N Menon, V Mariappan, KM Vellasamy… - Access …, 2020 - microbiologyresearch.org
Burkholderia pseudomallei is the causative agent for melioidosis. Because of its intracellular
nature, the bacterium is capable of replicating within a plethora of eukaryotic cell lines. B …

Different expression of Blimp-1 in HIV infection may be used to monitor disease progression and provide a clue to reduce immune activation and viral reservoirs

F Nicoli, F Sforza, R Gavioli - AIDS, 2015 - journals.lww.com
2. Larsson M, Shankar EM, Che KF, Saeidi A, Ellegard R, Barathan M, et al. Molecular
signatures of T-cell inhibition in HIV-1 infection. Retrovirology 2013; 10: 31. 3. Thaventhiran …

ITP 病人外周血中T 细胞免疫抑制性受体Tim-3, LAG-3 和BTLA 的表达特点

钟隽, 陈少华, 张涛, 郁志, 卢育洪, 杨力建, 赖菁… - 中国免疫学杂志, 2016 - cqvip.com
免疫性血小板减少症(Immune thrombocyt-openia, ITP) 是一种自身免疫性出血性疾病, T
细胞免疫调控在ITP 的发生发展中起重要作用. 我们前期研究发现了ITP 中存在异常的TCR …

HIV-1 Induction of Tolerogenic DCs is Mediated by Cellular Interaction with Suppressive T Cells

C Svanberg, S Nyström, M Govender, P Bhattacharya… - bioRxiv, 2021 - biorxiv.org
HIV-1 infection gives rise to a multilayered immune impairment in most infected individuals.
The crosstalk between Dendritic cells and T cells plays an important part in the induction of …

[图书][B] Investigations into the Immunomodulatory Properties of SLAMF7 and ERAP1

P O'Connell - 2021 - search.proquest.com
Autoimmune diseases represent one of the most complex pathological conditions
recognized by modern medicine; however, through investigations of these conditions we not …

树突细胞的特征及其生物学功能的研究进展

闫静静, 张晓燕 - 微生物与感染, 2012 - cqvip.com
树突细胞(DC) 是已知功能最强大的专职抗原呈递细胞(APc), 能高效摄取, 加工并呈递抗原给T
细胞, 同时上调表达主要组织相容性复合物(MHc) Ⅰ, Ⅱ 类分子, 协同刺激分子和黏附分子, 为T …