Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …

Steroidogenesis, the processes by which cholesterol is converted to steroid hormones,
involves transport proteins, enzymes, redox partners and cofactors. Most steroidogenic …

Adrenal venous sampling is recommended by current guidelines to identify surgically
curable causes of hyperaldosteronism but remains markedly underused. Key factors …

Primary aldosteronism comprises subtypes that need different therapeutic strategies.
Adrenal vein sampling is recognised by Endocrine Society guidelines as the only reliable …

Several studies over the past 3 decades document a higher prevalence of primary
aldosteronism (PA) among hypertensive patients than generally presumed. PA exists as a …

Objective: We hypothesized that an adrenal vein sampling (AVS) algorithm incorporating
rapid cortisol assays, which enables resampling of the adrenal veins, would improve the …

Serum steroid assays are major tools in the clinical evaluation of adrenal disorders. The
main adrenal steroids are routinely measured with immunoassays. However …

Abstract Context: 18-Oxocortisol (18-oxoF) is a derivative of cortisol (F) that is produced by
aldosterone synthase (CYP11B2). The potential for this steroid as a biomarker for …

Background In patients with primary hyperaldosteronism, adrenal vein sampling (AVS) has
emerged as a gold standard for distinguishing between unilateral and bilateral disease, but …

Update in adrenal venous sampling for primary aldosteronism : Current Opinion in Endocrinology,
Diabetes and Obesity Update in adrenal venous sampling for primary aldosteronism : Current …