The specialized pro-resolving lipid mediator Protectin D1 affects macrophages differentiation and activity in Adult-onset Still's disease and COVID-19, two …

L Navarini, M Vomero, D Currado… - Frontiers in …, 2023 - frontiersin.org
Introduction COVID-19 and autoinflammatory diseases, such as Adult-onset Still's Disease
(AOSD), are characterized by hyperinflammation, in which it is observed massive production …

Antiviral potential of rosuvastatin and hesperidin in combination with favipiravir liposomal nanoformulations in targeting the main protease (Mpro) of SARS-CoV-2 …

H Elimam, HS El-Sawy, MAA Fayed… - Journal of Drug Delivery …, 2024 - Elsevier
Favipiravir (Fav) is a drug utilized to treat coronavirus disease 2019 (COVID-19) due its
capacity to expedite the clearance of the SARS-CoV-2 virus through binding to its main …

The effect of reparixin on survival in patients at high risk for in-hospital mortality: a meta-analysis of randomized trials

G Landoni, A Zangrillo, G Piersanti… - Frontiers in …, 2022 - frontiersin.org
Introduction A great number of anti-inflammatory drugs have been suggested in the
treatment of SARS-CoV-2 infection. Reparixin, a non-competitive allosteric inhibitor of the …

The Effect of Rivaroxaban on CYP4F2 and Transcription Factors' Activity in HUVECs

I Ciapiene, V Tatarunas, A Giedraitiene, V Zvikas… - Applied Sciences, 2021 - mdpi.com
Interindividual variabilities between patients taking the anticoagulant rivaroxaban are a
result of hepatic metabolism by CYP 450 enzymes. The objective of this study was to …

[HTML][HTML] Qingfei Paidu Decoction Inhibits LPS-induced Acute Lung Injury by Targeting the Complement Pathway

D Shi, L Ge, L Yan, Y Zhang, T Wang… - … and Hypothesis in …, 2023 - xiahepublishing.com
Methods After the administration of QFPD treatment in LPS-induced ALI mice, the
therapeutic effect was evaluated through the H&E staining of lung tissues and the level of …

Exploration of Repositioned Drugs in the Management of Renal Ischemia Reperfusion Injury

S Ravichandran - 2023 - search.proquest.com
Recent evidence demonstrates that oxygenated perfusion at 22 C is superior to static cold
storage for preserving pre-transplanted kidneys; nonetheless, there is opportunity for …