The incidence and prevalence of heart failure with preserved ejection fraction (HFpEF)
continue to rise in tandem with the increasing age and burdens of obesity, sedentariness …

Heart failure with preserved ejection fraction is an increasing challenge for modern day
medicine and has been drawing more attention recently. Invasive right heart catheterization …

Aims Ancillary analyses from clinical trials have suggested reduced efficacy for
neurohormonal antagonists among patients with heart failure and preserved ejection …

Background Many therapies for heart failure (HF) have shown differential impact across the
spectrum of left ventricular ejection fraction (LVEF). Objectives In this prespecified analysis …

Congestive heart failure (HF) is a complex disease state characterized by impaired
ventricular function and insufficient peripheral blood supply. The resultant reduced blood …

Heart failure with preserved ejection fraction (HFpEF) is a major driver of cardiac morbidity
and mortality in developed countries, due to ageing populations and the increasing …

Aims Pulmonary capillary wedge pressure (PAWP)≥ 25 mmHg during bicycle ergometry is
recommended to uncover occult heart failure with preserved ejection fraction. We …

A reclassification of heart failure based on recognition of heart failure with normal to
supernormal ejection fraction, a clinically common form of cardiac contracture, with …

Aims Newly introduced drugs for heart failure (HF) have been reported to improve the
prognosis of HF with preserved ejection fraction (HFpEF) in the lower range of left ventricular …

Highlights•Supra-normal left ventricular ejection fraction is a new concept possibly
associated with U-shaped prognosis.•Heart failure with supra-normal ejection fraction …