Severe outcomes of COVID-19 among patients with multiple sclerosis under anti-CD-20 therapies: a systematic review and meta-analysis

I Schiavetti, M Ponzano, A Signori, F Bovis… - Multiple Sclerosis and …, 2022 - Elsevier
Background COVID-19 may spread through various ways ranging from asymptomatic to
severe forms, until respiratory failure, critical conditions and death occurs. There is a …

Real‐world evaluation of ocrelizumab in multiple sclerosis: A systematic review

X Montalban, PM Matthews, A Simpson… - Annals of clinical …, 2023 - Wiley Online Library
Across its clinical development program, ocrelizumab demonstrated efficacy in improving
clinical outcomes in multiple sclerosis, including annualized relapse rates and confirmed …

[HTML][HTML] Predictors of ocrelizumab effectiveness in patients with multiple sclerosis

M Cellerino, G Boffa, C Lapucci, F Tazza, E Sbragia… - …, 2021 - Elsevier
Data regarding effectiveness and safety of ocrelizumab in the post-marking setting are
lacking. The aim of our study was to provide effectiveness and safety data of ocrelizumab …

Effectiveness of ocrelizumab in primary progressive multiple sclerosis: a multicenter, retrospective, real-world study (OPPORTUNITY)

CG Chisari, A Bianco, VB Morra, M Calabrese… - …, 2023 - Elsevier
Ocrelizumab is a recombinant humanized monoclonal antibody selectively targeting CD20-
expressing B cells. The effect of ocrelizumab on primary progressive multiple sclerosis …

Predicting infection risk in multiple sclerosis patients treated with ocrelizumab: a retrospective cohort study

N Seery, S Sharmin, V Li, AL Nguyen, C Meaton… - CNS drugs, 2021 - Springer
Background Ocrelizumab safety outcomes have been well evaluated in clinical trials and
open-label extension (OLE) studies. However, risk factors for infection in patients with …

Ocrelizumab treatment in multiple sclerosis: a Danish population‐based cohort study

L Pontieri, M Blinkenberg, S Bramow… - European Journal of …, 2022 - Wiley Online Library
Background and purpose Real‐world evidence regarding the effectiveness and safety of
ocrelizumab for the treatment of multiple sclerosis (MS) is limited. The aim was to evaluate …

SARS-CoV-2 infection in multiple sclerosis patients: interaction with treatments, adjuvant therapies, and vaccines against COVID-19

A Muñoz-Jurado, BM Escribano, E Agüera… - Journal of …, 2022 - Springer
The SARS-CoV-2 pandemic has raised particular concern for people with Multiple Sclerosis,
as these people are believed to be at increased risk of infection, especially those being …

A systematic review of the safety and efficacy of monoclonal antibodies for progressive multiple sclerosis

Z Sabahi, AD Sorkhabi, A Sarkesh, A Naseri… - International …, 2023 - Elsevier
Background Progressive multiple sclerosis (PMS) is a debilitating condition characterized by
progressively worsening symptoms. Monoclonal antibodies are novel therapies for MS, but …

Treatment Patterns and Unmet Need for Patients with Progressive Multiple Sclerosis in the United States: Survey Results from 2016 to 2021

C Watson, D Thirumalai, A Barlev, E Jones… - Neurology and …, 2023 - Springer
Introduction Much of the current literature on treatment patterns and disability progression in
multiple sclerosis (MS) does not distinguish between the relapsing–remitting and …

Adherence to and persistence with disease-modifying therapies for multiple sclerosis over 24 months: a retrospective claims analysis

G Pardo, ED Pineda, CD Ng, KK Bawa… - Neurology and …, 2022 - Springer
Introduction We sought to assess adherence to and persistence with ocrelizumab (OCR)
compared with other disease-modifying treatments (DMTs), by route of administration (RoA) …