Targeted therapies in psoriatic arthritis—an update

S Sundanum, C Orr, D Veale - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriatic arthritis (PsA) is a systemic inflammatory condition characterised by multiple
clinical manifestations. Over the last decade, significant progress has been made in …

The role of IL‐23 and the use of IL‐23 inhibitors in psoriatic arthritis

GE Fragoulis, S Siebert - Musculoskeletal Care, 2022 - Wiley Online Library
Abstract Background Psoriatic arthritis (PsA) is a chronic inflammatory arthritis characterised
by musculoskeletal and extra‐articular manifestations, most notably psoriasis. While the …

A clinical review of structural damage in psoriatic arthritis for dermatologists: from pathogenesis to ongoing controversies

JF Merola, SD Chakravarty, O Choi, D Chan… - Journal of the American …, 2023 - Elsevier
Psoriatic arthritis (PsA) is a chronic inflammatory disease that often goes unrecognized in
patients with psoriasis. As a result, patients may develop significant structural damage …

Microscopic colitis and risk of incident rheumatoid arthritis: a nationwide population‐based matched cohort study

D Bergman, B Roelstraete, J Sun… - Alimentary …, 2023 - Wiley Online Library
Background Microscopic colitis (MC) has been linked to several autoimmune conditions.
Results from previous studies on the association with rheumatoid arthritis (RA) have been …

Interleukin-23 Involved in Fibrotic Autoimmune Diseases: New Discoveries

M Sisto, S Lisi - Journal of Clinical Medicine, 2023 - mdpi.com
Interleukin (IL)-23 is a central pro-inflammatory cytokine with a broad range of effects on
immune responses. IL-23 is pathologically linked to the induction of the production of the pro …

Spondyloarthropathy in Inflammatory Bowel Disease: From Pathophysiology to Pharmacological Targets

F Crispino, M Grova, EM Bruno, N Monachino, G Rizzo… - Drugs, 2022 - Springer
Spondyloarthritis (SpA) represents one of the most frequent extraintestinal manifestations of
inflammatory bowel disease (IBD). Evidence of shared genetic and molecular pathways …

IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy

JG Krueger, K Eyerich, VK Kuchroo… - Frontiers in …, 2024 - frontiersin.org
Interleukin (IL)-23, an IL-12 cytokine family member, is a hierarchically dominant regulatory
cytokine in a cluster of immune-mediated inflammatory diseases (IMIDs), including psoriasis …

Inflammatory cytokines in psoriatic arthritis: understanding pathogenesis and implications for treatment

BW Lee, SJ Moon - International journal of molecular sciences, 2023 - mdpi.com
Psoriatic arthritis (PsA) is a persistent, inflammatory disease that affects individuals with
psoriasis, arthritis, and enthesitis. Research has demonstrated that inflammatory cytokines …

[HTML][HTML] Перспективы применения моноклональных антител к интерлейкину 23 гуселькумаба при псориатическом артрите: новые данные

ЕЛ Насонов, ТВ Коротаева, С Родолфи… - Научно-практическая …, 2022 - cyberleninka.ru
В спектре механизмов патогенеза иммуновоспалительных заболеваний (ИВЗ)
человека особое внимание привлечено к патологической активации Th17-типа …

[HTML][HTML] Guselkumab reduces disease-and mechanism-related biomarkers more than adalimumab in patients with psoriasis: a VOYAGE 1 substudy

A Blauvelt, RG Langley, PJ Branigan, X Liu, Y Chen… - JID Innovations, 2024 - Elsevier
Background Psoriasis is an immune-mediated inflammatory disease characterized by
activation of interleukin (IL)-23–driven IL-17–producing T cell and other IL-23 receptor+ IL …