Migraine: from pathophysiology to treatment

F Puledda, EM Silva, K Suwanlaong, PJ Goadsby - Journal of Neurology, 2023 - Springer
Migraine is an extremely disabling, common neurological disorder characterized by a
complex neurobiology, involving a series of central and peripheral nervous system areas …

Hormonal influences in migraine—interactions of oestrogen, oxytocin and CGRP

DN Krause, K Warfvinge, KA Haanes… - Nature Reviews …, 2021 - nature.com
Migraine is ranked as the second highest cause of disability worldwide and the first among
women aged 15–49 years. Overall, the incidence of migraine is threefold higher among …

Longitudinal neuroimaging over 30 days: temporal characteristics of migraine

LH Schulte, J Mehnert, A May - Annals of neurology, 2020 - Wiley Online Library
Objective Although migraine is defined by the headache and headache‐associated
symptoms, the true beginning of a migraine attack lies in the premonitory phase. To …

Dysregulation of serum prolactin links the hypothalamus with female nociceptors to promote migraine

M Watanabe, CM Kopruszinski, A Moutal, D Ikegami… - Brain, 2022 - academic.oup.com
Migraine headache results from activation of meningeal nociceptors, however, the
hypothalamus is activated many hours before the emergence of pain. How hypothalamic …

Parenchymal neuroinflammatory signaling and dural neurogenic inflammation in migraine

ŞE Erdener, Z Kaya, T Dalkara - The journal of headache and pain, 2021 - Springer
Background Pain is generally concomitant with an inflammatory reaction at the site where
the nociceptive fibers are activated. Rodent studies suggest that a sterile meningeal …

Physical therapy and migraine: musculoskeletal and balance dysfunctions and their relevance for clinical practice

GF Carvalho, A Schwarz, TM Szikszay… - Brazilian journal of …, 2020 - Elsevier
Background Migraine is a primary headache with high levels of associated disability that can
be related to a variety of symptoms and comorbidities. The role of physical therapy in the …

Aura phenomena do not initiate migraine attacks—Findings from neuroimaging

J Mehnert, L Fischer‐Schulte… - Headache: The Journal of …, 2023 - Wiley Online Library
Abstract Objectives/Background As cortical spreading depolarization (CSD) has been
suggested to be the cause of migraine aura and as CSD can activate trigeminal nociceptive …

ATP-sensitive potassium channels in migraine: translational findings and therapeutic potential

A Clement, S Guo, I Jansen-Olesen, SL Christensen - Cells, 2022 - mdpi.com
Globally, migraine is a leading cause of disability with a huge impact on both the work and
private life of affected persons. To overcome the societal migraine burden, better treatment …

[HTML][HTML] Migraine attacks as a result of hypothalamic loss of control

A Stankewitz, L Keidel, M Rehm, S Irving… - NeuroImage: Clinical, 2021 - Elsevier
Migraine is a complex neurological disorder affecting approximately 12% of the population.
The pathophysiology is not yet fully understood, however the clinical features of the disease …

Visual snow syndrome, the spectrum of perceptual disorders, and migraine as a common risk factor: a narrative review

A Klein, CJ Schankin - Headache: The Journal of Head and …, 2021 - Wiley Online Library
Objective The aim of this narrative review is to explore the relationship between visual snow
syndrome (VSS), migraine, and a group of other perceptual disorders. Background VSS is …