Recent advances in our understanding of the contribution of thrombin generation to arterial
thrombosis and the role of platelets in venous thrombosis have prompted new treatment …

The duration of dual antiplatelet therapy (DAPT) after coronary stenting has been evaluated
in randomized studies with apparently conflicting results. Although longer exposure …

Background Combination antiplatelet therapy with clopidogrel and aspirin may reduce the
rate of recurrent stroke during the first 3 months after a minor ischemic stroke or transient …

This report presents the recommendations of the WHO Expert Committee responsible for
updating the WHO Model Lists of Essential Medicines.. The goal of the meeting was to …

Background—Recent studies have raised concerns about the reduced efficacy of
clopidogrel when used concurrently with proton pump inhibitors (PPIs), but those studies …

BACKGROUND & AIMS: We performed a meta-analysis of data from randomized trials to
estimate the risk of all-cause mortality and bleeding (and especially gastrointestinal [GI] …

Background: In patients with acute minor ischemic stroke or high-risk transient ischemic
attack enrolled in the POINT trial (Platelet-Oriented Inhibition in New TIA and Minor Ischemic …

Background: Several recent guidelines recommend assessment of patients with TIA within
24 hours, but it is uncertain how many recurrent strokes occur within 24 hours. It is also …

Background Antiplatelet therapy is the standard treatment for the prevention of
cardiovascular events (CVEs). High on‐treatment platelet reactivity (HPR) is a risk factor for …

Background Aspirin is the prophylactic antiplatelet drug of choice for people with
cardiovascular disease. Adding a second antiplatelet drug to aspirin may produce additional …