Streptococcus pneumoniae is an important human pathogen. Currently used conjugate
vaccines are effective against invasive disease, but protection is restricted to serotypes …

Abstract Angiotensin-converting enzyme 2 (ACE2) is responsible for cell fusion with SARS-
CoV viruses. ACE2 is contained in different areas of the human body, including the nasal …

The purpose of this study was to prepare large hollow particles (LHPs) by spray drying for
pulmonary delivery of cyclosporine A (CsA), using L-Leucine (LEU) and hydroxypropyl …

Introduction Dry powder inhaler (DPI) formulations are gaining attention as universal
formulations with applications in a diverse range of drug formulations. The practical …

Resveratrol (RSV) is a bioactive phytoconstituent that has potential applications in
respiratory diseases. However, poor oral bioavailability is the major hurdle to its clinical use …

Pseudomonas aeruginosa (PA), a predominant pathogen in lung infections, poses
significant challenges due to its biofilm formation, which is the primary cause of chronic and …

Background There is a growing interest in the use of dry powder inhalers (DPIs) for
administering high-dose drugs with low potency to the lungs as carrier-free formulations to …

Respirable particles are integral to effective inhalable therapeutic ingredient delivery,
demanding precise engineering for optimal lung deposition and therapeutic efficacy. This …

Mycobacterium tuberculosis (M. tb) has infected one-quarter of the world's population and
led to the deaths of 1.6 million individuals in 2021 according to estimates from the World …

Nanotechnology has expanded in drug delivery applications in recent years due to inherent
features such as drug compatibility, improved solubility/bioavailability of poorly soluble …