[HTML][HTML] Do soft mist inhalers hold the key to faster inhalation drug development?

W de Kruijf, B Müllinger - ONdrugDelivery, 2022 - ondrugdelivery.com
The rise of the biopharmaceutical segment has increased the value of the inhalation sector,
with more and more drug developers exploring inhalation as an alternative delivery …

Inhaled insulin: current steps towards diabetes treatment

P Patel, B Kacha - International Journal of Nano and …, 2024 - inderscienceonline.com
Diabetes mellitus is among the most serious health challenges worldwide. Diabetes is a
chronic condition that develops when the pancreas fails to adequately make or utilise …

[PDF][PDF] Dry powder inhalers in the digitalization era: current status and future perspectives. Pharmaceutics. 2021; 13: 1455

S Xiroudaki, A Schoubben, S Giovagnoli, DM Rekkas - 2021 - academia.edu
During the last decades, the term “drug delivery systems”(DDSs) has almost fully replaced
previously used terms, such as “dosage forms”, in an attempt to emphasize the importance …

Utilizing solid-state techniques and accelerated conditions to understand particle size instability in inhaled drug substances

DP Dobson, E Yanez, JW Lubach, A Stumpf… - Journal of …, 2021 - Elsevier
Micronization by air jet milling is often used to produce drug substance particles of
acceptable respirable size for use in dry powder inhaler formulations. The energy from this …

Quality Control of Industrially Manufactured Particulate Formulation by Particle Counting Approach

Y Wang, H Wang, S Wang, H Qin, P Zhou - Colloid Journal, 2023 - Springer
After more than two decades of development, particulate formulations have gradually
entered the industrialization stage, and their quality control is important. In the manufacturing …

Advancements in Metered-Dose Inhaler Technology: Feasibility of Excipients and Particle Size Prediction

Z Minootan - 2024 - era.library.ualberta.ca
Chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD) are
one of the leading causes of death in the world. According to the World Health Organization …

Dry powder for inhalation of single and fixed dose combinations of nintedanib, pirfenidone and mycophenolic acid prepared by thin-film freezing technology

T Praphawatvet - 2023 - repositories.lib.utexas.edu
Dry powder for inhalation (DPI) exhibits a non-invasive drug delivery that has been
developed to achieve the therapeutic efficacies and undesirable side effects of oral …

Effects of Buffer Composition on DNase I Formulation in Disordered Mesoporous Silica Particles

L Startaite - 2024 - diva-portal.org
Cystic fibrosis, a genetic disorder affecting multiple organs in the body, including the lungs,
remains a significant threat to patients due to inadequate treatment options. Treatment …

[PDF][PDF] Inhaled ciprofloxacin-loaded poly (2-ethyl-2-oxazoline) nanoparticle dry powder inhaler formulation for the management of lower respiratory tract infections

MZR Sabuj - 2023 - eprints.qut.edu.au
This project developed inhaled antibiotic-loaded polymer nanoparticulate dry powder
inhaler (DPI) formulation for managing lower respiratory tract infections (LRTIs). It …

[PDF][PDF] Inhaled RNA Therapeutics for Obstructive Airway Diseases: Recent Advances and Future Prospects. Pharmaceutics 2021, 13, 177

Y Xu, A Thakur, Y Zhang, C Foged - 2021 - academia.edu
Obstructive airway diseases, eg, chronic obstructive pulmonary disease (COPD) and
asthma, represent leading causes of morbidity and mortality worldwide. However, the …