Idiopathic nephrotic syndrome is the most common glomerular disease in children.
Corticosteroids are the cornerstone of its treatment, and steroid response is the main …

Lupus nephritis is an important manifestation of systemic lupus erythematosus, which leads
to chronic kidney disease, kidney failure, and can result in mortality. About 35%–60% of …

Background Long-term data pertaining to rituximab as add-on therapy in childhood-onset
lupus nephritis (cLN) is scarce. Methods A retrospective cohort study was conducted on all …

B-cell depleting anti-CD20 monoclonal antibodies, such as rituximab, have proven efficacy
in children with frequently-relapsing/steroid-dependent nephrotic syndrome (FR/SDNS) …

Objectives There is little data on renal relapse in childhood-onset LN (cLN). We investigate
the incidence, predictive factors and outcomes related to renal relapse. Methods We …

Immunosuppressants are commonly used as steroid-sparing agents in childhood idiopathic
nephrotic syndrome (NS) to induce and sustain remissions. These drugs have narrow …

Background purpose Rituximab (RTX), an anti-CD20 monoclonal antibody can effectively
treat minimal change disease (MCD), with low toxicity and a reduced steroid dosage. The …

Most of the immunologic or non-immunologic renal diseases have a bad prognosis without
treatment, and the treatment is complicated in these diseases. With the introduction of …

Gomes et al. 1 present in the current issue of BJN a report on the promising outcomes
achieved with the use of rituximab (RTX) in 16 pediatric and adolescent nephrotic patients …

Idiopathic nephrotic syndrome (iNS) is the most common glomerular disease in childhood
and there are clear and generally accepted treatment strategies for initial and follow-up …