Since 2020, the highly contagious nature and various transmission routes of SARS-CoV-2
have rendered the pandemic interminable. Vertical transmission through the placenta and …

Highlights•Human pluripotent stem cells possess differentiation potency into trophoblast
lineage.•Naive human pluripotent stem cells differentiate into trophoblasts via …

This review focuses on SARS-CoV-2 infection in placental and fetal tissues. Viremia is rare
in infected pregnant women, and the virus is seldom amplified from placental tissues …

The type-I interferon (IFN) response constitutes the major innate immune pathway against
viruses in mammals. Despite its critical importance for antiviral defence, this pathway is …

Several studies have reported vertical transmission of SARS-CoV-2; however, information
regarding intrauterine transmission based on diagnostic methods to detect SARS-CoV-2 …

Pre‐eclampsia and fetal growth restriction (FGR) continue to cause unacceptably high levels
of morbidity and mortality, despite significant pharmaceutical and technological advances in …

Preeclampsia is one of the most common disorders that poses threat to both mothers and
neonates and a major contributor to perinatal morbidity and mortality worldwide. Viral …

Background SARS-CoV-2 infection during pregnancy increases the risk of severe obstetrical
complications. Detailed evaluation of COVID-19-associated coagulopathy in a pregnancy …

Background Several observational studies demonstrated that pregnant individuals with
COVID-19 had a higher risk of preeclampsia and preterm birth. We aimed to determine …

The COVID-19 pandemic has had a significant and enduring influence on global health,
including maternal and fetal well-being. Evidence suggests that placental dysfunction is a …