Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer

AW Caliri, S Tommasi, A Besaratinia - Mutation Research/Reviews in …, 2021 - Elsevier
Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …

[HTML][HTML] Vitamin D modulates intestinal microbiota in inflammatory bowel diseases

C Battistini, R Ballan, ME Herkenhoff… - International journal of …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic inflammation of the gastrointestinal tract (GIT),
including Crohn's disease (CD) and ulcerative colitis (UC), which differ in the location and …

Genetics and epigenetics of IBD

V Annese - Pharmacological research, 2020 - Elsevier
Inflammatory bowel diseases (IBD) are chronic intermittent inflammatory disorders of the
gastrointestinal tract of unknown etiology but a clear genetic predisposition. Prompted by the …

Calprotectin in inflammatory bowel disease

F Khaki-Khatibi, D Qujeq, M Kashifard, S Moein… - Clinica chimica acta, 2020 - Elsevier
The term IBD is usually used for referring to a group of inflammatory gastro-intestinal
diseases (mainly Crohn's disease and ulcerative colitis). Accordingly, IBD arises as a result …

[HTML][HTML] Genetic and epigenetic etiology of inflammatory bowel disease: An update

S Jarmakiewicz-Czaja, M Zielińska, A Sokal, R Filip - Genes, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic disease with periods of exacerbation and
remission of the disease. The etiology of IBD is not fully understood. Many studies point to …

Molecular basis of vitamin D action in inflammatory bowel disease

C Triantos, I Aggeletopoulou, GJ Mantzaris… - Autoimmunity …, 2022 - Elsevier
There is growing evidence of vitamin D involvement in immune regulation and gut barrier
function, suggesting that vitamin D may play a critical role in the development of …

[HTML][HTML] The role of epigenetic modifications for the pathogenesis of Crohn's disease

M Hornschuh, E Wirthgen, M Wolfien, KP Singh… - Clinical …, 2021 - Springer
Epigenetics has become a promising field for finding new biomarkers and improving
diagnosis, prognosis, and drug response in inflammatory bowel disease. The number of …

Results of the seventh scientific workshop of ECCO: precision medicine in IBD—what, why, and how

C Fiocchi, G Dragoni, D Iliopoulos… - Journal of Crohn's …, 2021 - academic.oup.com
Many diseases that affect modern humans fall in the category of complex diseases, thus
called because they result from a combination of multiple aetiological and pathogenic …

[HTML][HTML] STAT1 epigenetically regulates LCP2 and TNFAIP2 by recruiting EP300 to contribute to the pathogenesis of inflammatory bowel disease

YL Yu, M Chen, H Zhu, MX Zhuo, P Chen, YJ Mao… - Clinical …, 2021 - Springer
Background The aetiology of inflammatory bowel disease (IBD) is related to genetics and
epigenetics. Epigenetic regulation of the pathogenesis of IBD has not been well defined …

[HTML][HTML] Harnessing the power of precision medicine and novel biomarkers to treat Crohn's disease

OA Kriger-Sharabi, U Kopylov - Journal of Clinical Medicine, 2023 - mdpi.com
Crohn's disease (CD) is a chronic inflammatory condition that affects the gastrointestinal
tract. It is part of a spectrum of inflammatory Bowel Diseases (IBD). The disease is complex …