Management of complicated diaphragmatic hernia in the acute setting: a WSES position paper

M Giuffrida, G Perrone, F Abu-Zidan, V Agnoletti… - World Journal of …, 2023 - Springer
Background Diaphragmatic hernia (DH) presenting acutely can be a potentially life-
threatening condition. Its management continues to be debatable. Methods A bibliographic …

Effects of spinal deformities on lung development in children: a review

Y Wang, D Wang, G Zhang, B Ma, Y Ma, Y Yang… - Journal of Orthopaedic …, 2023 - Springer
Scoliosis before the age of 5 years is referred to as early-onset scoliosis (EOS). While
causes may vary, EOS can potentially affect respiratory function and lung development as …

Diagnosis & management of pulmonary hypertension in congenital diaphragmatic hernia

S Bhombal, N Patel - Seminars in Fetal and Neonatal Medicine, 2022 - Elsevier
Congenital diaphragmatic hernia (CDH) contributes to neonatal morbidity and mortality
worldwide. Pulmonary hypertension (PH) is a key component of CDH pathophysiology and …

The etiology of congenital diaphragmatic hernia: the retinoid hypothesis 20 years later

JFG Rivas, RD Clugston - Pediatric Research, 2024 - nature.com
Congenital diaphragmatic hernia (CDH) is a severe birth defect and a major cause of
neonatal respiratory distress. Impacting~ 2–3 in 10,000 births, CDH is associated with a high …

Sildenafil during the 2nd and 3rd Trimester of Pregnancy: Trials and Tribulations

FR De Bie, D Basurto, S Kumar, J Deprest… - International Journal of …, 2022 - mdpi.com
Sildenafil, a phosphodiesterase 5 inhibitor with a vasodilatory and anti-remodeling effect,
has been investigated concerning various conditions during pregnancy. Per indication, we …

Connecting clinical, environmental, and genetic factors point to an essential role for vitamin A signaling in the pathogenesis of congenital diaphragmatic hernia

RM Gilbert, JP Gleghorn - American Journal of Physiology …, 2023 - journals.physiology.org
Congenital diaphragmatic hernia (CDH) is a developmental disorder that results in
incomplete diaphragm formation, pulmonary hypoplasia, and pulmonary hypertension …

Treatment with amniotic fluid stem cell extracellular vesicles promotes fetal lung branching and cell differentiation at canalicular and saccular stages in experimental …

K Khalaj, RL Figueira, L Antounians… - Stem cells …, 2022 - academic.oup.com
Pulmonary hypoplasia secondary to congenital diaphragmatic hernia (CDH) is
characterized by impaired branching morphogenesis and differentiation. We have …

[HTML][HTML] Recent advances in the treatment of complex congenital diaphragmatic hernia—a narrative review

KI Holden, MT Harting - Translational Pediatrics, 2023 - ncbi.nlm.nih.gov
Methods PubMed was searched in late 2022 and early 2023 to identify relevant evidence.
Search terms included congenital diaphragmatic hernia (CDH)”,“extracorporeal life support …

Single-cell guided prenatal derivation of primary fetal epithelial organoids from human amniotic and tracheal fluids

MFM Gerli, G Calà, MA Beesley, B Sina, L Tullie… - Nature Medicine, 2024 - nature.com
Isolation of tissue-specific fetal stem cells and derivation of primary organoids is limited to
samples obtained from termination of pregnancies, hampering prenatal investigation of fetal …

Exploring new perspectives on congenital diaphragmatic hernia: A comprehensive review

W Renik-Jankowska, A Buczyńska… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Congenital diaphragmatic hernia (CDH) represents a developmental anomaly that
profoundly impacts the embryonic development of both the respiratory and cardiovascular …