The nucleotide-binding, oligomerization domain-like receptor family pyrin domain containing
3 (NLRP3) inflammasome is a multiprotein complex that combines sensing, regulation, and …

Inhalation of silica particles is an environmental and occupational cause of silicosis, a type
of pneumoconiosis. Development of the lung silicosis is a unique process in which the …

Rationale: Tolerogenic dendritic cells (tol-DCs) play essential roles in immune-related
diseases and induce immune tolerance by shaping T-cell responses. Accumulating …

The NLRP3 inflammasome is implicated in the processing of the pro-inflammatory cytokine
interleukin 1β. Inflammatory disorders associated with the activation of the NLRP3 …

Several lines of evidence point out the relevance of nucleotide-binding oligomerization
domain leucine-rich repeat and pyrin domain-containing protein 3 (NLRP3) inflammasome …

Medicinal plants are a vital source of natural products (NPs) that can cure cancer through
modulation of different pathways, including oxidative stress, extrinsic and intrinsic apoptosis …

Background Chaiqin chengqi decoction (CQCQD) is a Chinese herbal formula derived from
dachengqi decoction. CQCQD has been used for the management of acute pancreatitis (AP) …

Sepsis was known to ancient Greeks since the time of great physician Hippocrates (460–
377 BC) without exact information regarding its pathogenesis. With time and medical …

The NLRP3 inflammasome holds a crucial role in innate immune responses. Pathogen-and
danger-associated molecular patterns may initiate inflammasome activation and following …

The immune system contributes to the regulation of pregnancy, and the disruption of well-
controlled immune functions leads to pregnancy complications. Recently, the nucleotide …