Regulated cell death pathways in kidney disease

AB Sanz, MD Sanchez-Niño, AM Ramos… - Nature Reviews …, 2023 - nature.com
Disorders of cell number that result from an imbalance between the death of parenchymal
cells and the proliferation or recruitment of maladaptive cells contributes to the pathogenesis …

The impact of toxic metal bioaccumulation on colorectal cancer: unravelling the unexplored connection

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of the Total …, 2023 - Elsevier
Colorectal cancer is a major public health concern, with increasing incidence and mortality
rates worldwide. Environmental factors, including exposure to toxic metals, such as lead …

[HTML][HTML] Aluminium bioaccumulation in colon cancer, impinging on epithelial-mesenchymal-transition and cell death

R Bonfiglio, R Sisto, S Casciardi, V Palumbo… - Science of The Total …, 2024 - Elsevier
We investigated the presence of aluminium (Al) in human colon cancer samples and its
potential association with biological processes involved in cancer progression, such as …

Identification and validation of a ferroptosis-related lncRNA signature to robustly predict the prognosis, immune microenvironment, and immunotherapy efficiency in …

L Ju, Y Shi, G Liu - PeerJ, 2022 - peerj.com
Background Ferroptosis is a new type of iron-and reactive oxygen species-dependent cell
death, studies on ferroptosis-related long noncoding RNAs (FerLncRNAs) in clear cell renal …

The emerging role of long non-coding RNAs in renal cell carcinoma progression and clinical therapy via targeting metabolic regulation

X Gao, H Zhang, C Zhang, M Li, X Yu, Y Sun… - Frontiers in …, 2023 - frontiersin.org
Renal cell carcinoma (RCC) is the most frequent renal malignancy in the world, and its
incidence is increasing year by year. RCC is a well-known drug resistant tumor, and the …

Programmed Cell Death Pathways in Cholangiocarcinoma: Opportunities for Targeted Therapy

M Scimeca, V Rovella, V Palumbo, MP Scioli… - Cancers, 2023 - mdpi.com
Simple Summary Cholangiocarcinoma is a highly aggressive cancer that originates from the
bile ducts. Traditional treatments have limited effectiveness, necessitating the exploration of …

[HTML][HTML] Targeting apoptosis in clear cell renal cell carcinoma

A Kowalewski, J Borowczak, M Maniewski… - Biomedicine & …, 2024 - Elsevier
Clear cell renal cell carcinoma (ccRCC) is the most prevalent subtype of renal cancer,
accounting for approximately 80% of all renal cell cancers. Due to its exceptional inter-and …

A risk signature based on necroptotic-process-related genes predicts prognosis and immune therapy response in kidney cell carcinoma

J Li, X Liu, Y Qi, Y Liu, E Du, Z Zhang - Frontiers in Immunology, 2022 - frontiersin.org
Necroptosis is a regulated form of cell necroptotic process, playing a pivotal role in tumors.
In renal cell cancer (RCC), inhibiting necroptosis could promote the proliferation of tumor …

[HTML][HTML] Disulfideptosis-associated lncRNAs reveal features of prognostic, immune escape, tumor mutation, and tumor malignant progression in renal clear cell …

X Li, X Deng, T Liu, W Zhang, J Tao - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Purpose: Investigating the role of lncRNAs associated with the latest cell death mode
(Disulfideptosis) in renal clear cell carcinoma, as well as their correlation with tumor …

不同类型程序性细胞死亡途径在肾癌中的研究进展

吴明哲, 王富春, 潘浩杰, 周安安, 肖喜, 田俊强 - 肿瘤防治研究, 2023 - zlfzyj.com
程序性细胞死亡(PCD) 是机体内由遗传基因决定的细胞主动, 有序的死亡方式, 它在机体进化,
维持机体稳态以及多个组织器官的发育中发挥重要作用, 而这一过程的调控异常还与包括癌症在 …