Natural extracts have been and continue to be used to treat a wide range of medical
conditions, from infectious diseases to cancer, based on their convenience and therapeutic …

The network approach is quickly becoming a fundamental building block of computational
methods aiming at elucidating the mechanism of action (MoA) and therapeutic effect of …

Viral DNA and RNA polymerases are two kinds of very important enzymes that synthesize
the genetic materials of the virus itself, and they have become extremely favorable targets for …

Objectives The effectiveness of oseltamivir versus peramivir in children infected with
influenza remains unclear. This study aimed to evaluate their effectiveness in young children …

Despite the great technological and medical advances in fighting viral diseases, new
therapies for most of them are still lacking, and existing antivirals suffer from major limitations …

Viruses represent a major threat to human health and are capable of spreading either via
direct exposure or contamination of inanimate surfaces. Certain viruses have been shown to …

The emergence of drug-resistant Human Immunodeficiency Virus-1 strains against anti-HIV
therapies in the clinical pipeline, and the persistence of HIV in cellular reservoirs remains a …

Viruses, and in particular, RNA viruses, dominate the WHO's current list of ten global health
threats. Of these, we review the widespread and most common HIV, influenza virus, and …

Introduction Integrating interaction data with biological knowledge can be a critical approach
for drug development or drug repurposing. In this context, host-pathogen-protein-protein …

Pentacyclic aromatic hydrocarbon perylene is an easily derivatizable compound. Antiviral
properties of perylene derivatives and congeners (naturally occurring perylenquinones and …