An overview of FGF-23 as a novel candidate biomarker of cardiovascular risk

S Vázquez-Sánchez, J Poveda… - Frontiers in …, 2021 - frontiersin.org
Fibroblast growth factor-23 (FGF)-23 is a phosphaturic hormone involved in mineral bone
metabolism that helps control phosphate homeostasis and reduces 1, 25-dihydroxyvitamin …

[HTML][HTML] Therapeutic potential of targeting galectins–A biomaterials-focused perspective

S Martin-Saldana, MT Chevalier, A Pandit - Biomaterials, 2022 - Elsevier
Among all the biological entities involved in the immune response, galectins, a family of
glycan-binding proteins, have been described as key in immune cell homeostasis and …

Population serum proteomics uncovers a prognostic protein classifier for metabolic syndrome

X Cai, Z Xue, FF Zeng, J Tang, L Yue, B Wang… - Cell Reports …, 2023 - cell.com
Metabolic syndrome (MetS) is a complex metabolic disorder with a global prevalence of
20%–25%. Early identification and intervention would help minimize the global burden on …

Proteomics to improve phenotyping in obese patients with heart failure with preserved ejection fraction

KP Kresoja, KP Rommel, R Wachter… - European Journal of …, 2021 - Wiley Online Library
Aims Recent evidence points towards a distinct obese phenotype among patients with heart
failure with preserved ejection fraction (HFpEF). We aimed to identify differentially expressed …

Protein biomarkers of cardiac remodeling and inflammation associated with HFpEF and incident events

JA Regan, LK Truby, UA Tahir, DH Katz, M Nguyen… - Scientific reports, 2022 - nature.com
There is increasing evidence that HFpEF is a heterogeneous clinical entity and distinct
molecular pathways may contribute to pathophysiology. Leveraging unbiased proteomics to …

Identifying causal serum protein–cardiometabolic trait relationships using whole genome sequencing

G Png, R Gerlini, K Hatzikotoulas… - Human Molecular …, 2023 - academic.oup.com
Cardiometabolic diseases, such as type 2 diabetes and cardiovascular disease, have a high
public health burden. Understanding the genetically determined regulation of proteins that …

Red cell distribution width in patients with diabetes and myocardial infarction: an analysis from the EXAMINE trial

JP Ferreira, Z Lamiral, G Bakris, C Mehta… - Diabetes, Obesity …, 2021 - Wiley Online Library
Aim To determine the clinical correlates of increased red blood cell distribution width (RDW),
its potential mechanistic association with multiple circulating biomarkers, and its prognostic …

Prediction of heart failure outcomes in patients with type 2 diabetes mellitus: validation of the thrombolysis in myocardial infarction risk score for heart failure in …

M Elharram, JP Ferreira, T Huynh, J Ni… - Diabetes, Obesity …, 2021 - Wiley Online Library
Aim To investigate the ability of the Thrombolysis in Myocardial Infarction Risk Score for
Heart Failure in Diabetes (TRS‐HFDM) to stratify patients with type 2 diabetes mellitus …

Diabetes and heart failure: multi-omics approaches

A Tayanloo-Beik, PP Roudsari… - Frontiers in …, 2021 - frontiersin.org
Diabetes and heart failure, as important global issues, cause substantial expenses to
countries and medical systems because of the morbidity and mortality rates. Most people …

Association of plasma proteomics with incident coronary heart disease in individuals with and without type 2 diabetes: results from the population-based KORA study

H Luo, MT Huemer, A Petrera, SM Hauck… - Cardiovascular …, 2024 - Springer
Background Coronary heart disease (CHD) is a major global health concern, especially
among individuals with type 2 diabetes (T2D). Given the crucial role of proteins in various …