Anti-inflammatory and anticancer p-terphenyl derivatives from fungi of the genus Thelephora

C Bailly - Bioorganic & Medicinal Chemistry, 2022 - Elsevier
Fungi from the genus Thelephora have been exploited to identify bioactive compounds. The
main natural products characterized are para-terphenyl derivatives, chiefly represented by …

[HTML][HTML] In silico evaluation of antifungal compounds from marine sponges against COVID-19-associated mucormycosis

O Pokharkar, H Lakshmanan, G Zyryanov, M Tsurkan - Marine Drugs, 2022 - mdpi.com
The world is already facing the devastating effects of the SARS-CoV-2 pandemic. A
disseminated mucormycosis epidemic emerged to worsen this situation, causing havoc …

[HTML][HTML] Potency of Xanthone Derivatives from Garcinia mangostana L. for COVID-19 Treatment through Angiotensin-Converting Enzyme 2 and Main Protease …

C Suhandi, SS Alfathonah, AN Hasanah - Molecules, 2023 - mdpi.com
ACE2 and Mpro in the pathology of SARS-CoV-2 show great potential in developing COVID-
19 drugs as therapeutic targets, due to their roles as the “gate” of viral entry and viral …

Comprehensive Review on the Virulence Factors and Therapeutic Strategies with the Aid of Artificial Intelligence against Mucormycosis

M Tanwar, A Singh, TP Singh, S Sharma… - ACS Infectious …, 2024 - ACS Publications
Mucormycosis, a rare but deadly fungal infection, was an epidemic during the COVID-19
pandemic. The rise in cases (COVID-19-associated mucormycosis, CAM) is attributed to …

[HTML][HTML] Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma

I Morales-Salazar, CE Garduño-Albino… - Pharmaceuticals, 2023 - mdpi.com
An Ugi–Zhu three-component reaction (UZ-3CR) coupled in a one-pot manner to a cascade
process (N-acylation/aza Diels–Alder cycloaddition/decarboxylation/dehydration) was …

[HTML][HTML] Construction and validation of a multi-epitope in silico vaccine model for lymphatic filariasis by targeting Brugia malayi: a reverse vaccinology approach

P Madanagopal, S Muthusamy, SN Pradhan… - Bulletin of the National …, 2023 - Springer
Background Lymphatic filariasis (LF), often referred to as elephantiasis, has been identified
as one of the 17 neglected tropical diseases by the World Health Organization. Currently …

[HTML][HTML] Integrated in vivo and in silico evaluation of sweet basil oil as a protective agent against cisplatin-induced neurotoxicity in mice

DS Mohamed, O Shehata, MM Labib… - Beni-Suef University …, 2023 - Springer
Background Cisplatin is a wide-ranging antineoplastic drug. Neurotoxicity is one of
cisplatin's side effects that restrict its usage. This study aimed to investigate the possible …

[HTML][HTML] Combating black fungus: using allicin as a potent antifungal agent against mucorales

C Schier, MCH Gruhlke, G Reucher… - International Journal of …, 2023 - mdpi.com
Invasive fungal (IF) diseases are a leading global cause of mortality, particularly among
immunocompromised individuals. The SARS-CoV-2 pandemic further exacerbated this …

[HTML][HTML] Lipase-catalyzed synthesis, antioxidant activity, antimicrobial properties and molecular docking studies of butyl dihydrocaffeate

B Zieniuk, CJ Ononamadu, K Jasińska… - Molecules, 2022 - mdpi.com
Green chemistry approaches, such as lipase-catalyzed esterification, are promising methods
for obtaining valuable chemical compounds. In the case of the use of lipases, unlike in …

Evaluating Terrestrol A as an Inhibitor Against SARS‐CoV‐2and Invasive Fungal Pathogens: A Comprehensive Computational Analysis

B Singha, B Arora, R Karmaker, K Richa… - …, 2024 - Wiley Online Library
The highly contagious SARS‐CoV‐2 virus, which initiated the COVID‐19 pandemic, has
resulted in a significant loss of life worldwide. While vaccines and therapeutics have helped …