Long-chain polyunsaturated fatty acids regulation of PPARs, signaling: Relationship to tissue development and aging

F Echeverría, M Ortiz, R Valenzuela… - … Leukotrienes and Essential …, 2016 - Elsevier
Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors that function as
ligand-dependent transcription factors that can be activated by different types of fatty acids …

Therapeutic efficacies of berberine against neurological disorders: an update of pharmacological effects and mechanisms

JW Shou, PC Shaw - Cells, 2022 - mdpi.com
Neurological disorders are ranked as the leading cause of disability and the second leading
cause of death worldwide, underscoring an urgent necessity to develop novel …

[HTML][HTML] Modulation of PPAR signaling disrupts pancreas development in the zebrafish, Danio rerio

O Venezia, S Islam, C Cho, AR Timme-Laragy… - Toxicology and applied …, 2021 - Elsevier
Abstract Peroxisome Proliferator Activated Receptors (PPARs) are transcription factors that
regulate processes such as lipid and glucose metabolism. Synthetic PPAR ligands …

Effect of Galactooligosaccharide on PPARs/PI3K/Akt Pathway and Gut Microbiota in High-Fat and High-Sugar Diet Combined with STZ-Induced GDM Rat Model

J Wan, J Zhu, J Zeng, H Zhou, Y He - Probiotics and Antimicrobial Proteins, 2023 - Springer
Gestational diabetes mellitus (GDM) is a metabolic disorder, characterized by underlying
glucose intolerance, diabetes onset or first diagnosis during pregnancy …

Peroxisome Proliferator-Activated Receptors (PPAR), fatty acids and microRNAs: Implications in women delivering low birth weight babies.

DP Sundrani, AR Karkhanis… - Systems Biology in …, 2021 - Taylor & Francis
Low birth weight (LBW) babies are associated with neonatal morbidity and mortality and are
at increased risk for noncommunicable diseases (NCDs) in later life. However, the molecular …

Protein Dynamic Landscape of Pig Embryos during Peri-Implantation Development

X Zang, Q Huang, J Gan, L Jiang, F Meng… - Journal of Proteome …, 2024 - ACS Publications
Properly developed embryos are critical for successful embryo implantation. The dynamic
landscape of proteins as executors of biological processes in pig peri-implantation embryos …

Activation of PPAR δ: from computer modelling to biological effects

S Kahremany, A Livne, A Gruzman… - British journal of …, 2015 - Wiley Online Library
PPARδ is a ligand‐activated receptor that dimerizes with another nuclear receptor of the
retinoic acid receptor family. The dimers interact with other co‐activator proteins and form …

Low-concentration essential amino acids in PZM-3 improve the developmental competence of porcine embryos produced by handmade cloning

T Liu, J Li, H Dou, X Xiang, W Chen, T Zhang… - Cellular …, 2020 - liebertpub.com
Essential amino acids (EAA) of inappropriate concentration have been reported to
compromise the development of embryo. This study aimed to investigate the effect of EAA on …

Impact of polyunsaturated omega-6 and omega-3 fatty acids on cardiomyogenesis and vasculogenesis of mouse embryonic stem cells

AH Taha - 2022 - jlupub.ub.uni-giessen.de
PUFAs and their metabolites may influence differentiation processes of stem cells. The aim
of the current study was to determine the effects of LA as ω-6-PUFA and EPA as ω-3-PUFA …

Meta-pathway based analysis of stemness

SK Choudhary, V Kumar - 2022 - repository.iiitd.edu.in
Recent development in the field of stem cell research field has evoked the great
expectations. Researchers these days are full fledgedly working on developing methods to …