Applications of machine learning to diagnosis and treatment of neurodegenerative diseases

MA Myszczynska, PN Ojamies, AMB Lacoste… - Nature reviews …, 2020 - nature.com
Globally, there is a huge unmet need for effective treatments for neurodegenerative
diseases. The complexity of the molecular mechanisms underlying neuronal degeneration …

Social cognition through the lens of cognitive and clinical neuroscience

M Arioli, C Crespi, N Canessa - BioMed research international, 2018 - Wiley Online Library
Social cognition refers to a set of processes, ranging from perception to decision‐making,
underlying the ability to decode others' intentions and behaviors to plan actions fitting with …

[HTML][HTML] Interoception primes emotional processing: multimodal evidence from neurodegeneration

PC Salamone, A Legaz, L Sedeño… - Journal of …, 2021 - Soc Neuroscience
Recent frameworks in cognitive neuroscience and behavioral neurology underscore
interoceptive priors as core modulators of negative emotions. However, the field lacks …

A scoping review of neurodegenerative manifestations in explainable digital phenotyping

H Alfalahi, SB Dias, AH Khandoker… - npj Parkinson's …, 2023 - nature.com
Neurologists nowadays no longer view neurodegenerative diseases, like Parkinson's and
Alzheimer's disease, as single entities, but rather as a spectrum of multifaceted symptoms …

Clinical and radiological markers of extra-motor deficits in amyotrophic lateral sclerosis

F Christidi, E Karavasilis, M Rentzos, N Kelekis… - Frontiers in …, 2018 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is now universally recognized as a complex multisystem
disorder with considerable extra-motor involvement. The neuropsychological manifestations …

Empathy and theory of mind in Parkinson's disease: A meta-analysis

SP Coundouris, AG Adams, JD Henry - Neuroscience & Biobehavioral …, 2020 - Elsevier
In contrast to well-documented deficits in the core social cognitive domains of social
perception and theory of mind (ToM), how Parkinson's disease (PD) affects one's empathic …

Progression of socio-cognitive impairment from healthy aging to Alzheimer's dementia: A systematic review and meta-analysis

M Roheger, J Brenning, S Riemann, AK Martin… - Neuroscience & …, 2022 - Elsevier
Background Trajectories of decline across different socio-cognitive domains in healthy older
adults and in pathological aging conditions have not been investigated. This was addressed …

Oxytocin suppresses inflammatory responses induced by lipopolysaccharide through inhibition of the eIF-2α–ATF4 pathway in mouse microglia

T Inoue, H Yamakage, M Tanaka, T Kusakabe… - Cells, 2019 - mdpi.com
Microglia maintain brain homeostasis and modulate neuroinflammation and are implicated
in the pathogenesis of various neurological diseases such as Alzheimer's disease. In this …

Exploring the relationship between deficits in social cognition and neurodegenerative dementia: a systematic review

E Setién-Suero, N Murillo-García… - Frontiers in aging …, 2022 - frontiersin.org
Background Neurodegenerative diseases might affect social cognition in various ways
depending on their components (theory of mind, emotional processing, attribution bias, and …

Social cognition and social functioning in patients with amnestic mild cognitive impairment or Alzheimer's dementia

RPC Kessels… - Journal of …, 2021 - Wiley Online Library
The aim of the present study was to examine social cognition and social functioning in a
group of amnestic mild cognitive impairment (aMCI) and Alzheimer's dementia (AD) patients …