In recent years, genome-wide association study (GWAS) sample sizes have become larger,
the statistical power has improved and thousands of trait-associated variants have been …

Abstract βII spectrin, the most common isoform of non-erythrocyte spectrin, is a cytoskeleton
protein present in all nucleated cells. Interestingly, βII spectrin is essential for the …

The gene of transcriptional repressor GATA binding 1 (TRPS1), as an atypical GATA
transcription factor, has received considerable attention in a plethora of physiological and …

Pancreatic ductal adenocarcinoma (PDAC) is a malignant tumor with very poor prognosis.
Therefore, it is important to fully understand the molecular mechanism underlying its …

Psoriatic arthritis (PsA) is a unique immune-mediated disease with cutaneous and
osteoarticular involvement. However, only a few studies have explored the susceptibility of …

Background Clinical and epidemiological studies have suggested systemic lupus
erythematosus (SLE) and rheumatoid arthritis (RA) are comorbidities and common genetic …

Expression of microRNA‑21 in bone tissue and serum of patients with osteoporosis (OP) and
its involvement in the regulation of osteogenic differentiation of rat bone marrow …

The cellular complexity of the endochondral bone underlies its essential and pleiotropic
roles during organismal life. While the adult bone has received significant attention, we still …

Aims Clinical and epidemiological findings point to an association between type 2 diabetes
(T2D) and osteoporosis. Genome-wide association studies (GWASs) have been fruitful in …

Background Childhood overweight/obesity is a global public health concern. It is important
to identify its early-life risk factors. Maternal poor sleep is common in late pregnancy, and …