Thyroid hormones take major part in normal growth, development and metabolism. Over a
century of research has supported a relationship between thyroid hormones and the …

Thyroid function is central in the control of physiological and pathophysiological processes.
Studies in animal models and human research have determined that thyroid hormones …

Context: Thyroid hormones are essential for neurodevelopment from early pregnancy
onward. Yet population-based data on the association between maternal thyroid function in …

BACKGROUND: Tissue homeostasis depends on the balance between cell proliferation and
differentiation. Thyroid hormones (THs), through binding to their nuclear receptors, can …

Context: In vitro and in vivo experiments have assigned both oncosuppressive and
oncogenic properties to thyroid hormones. Population-based studies have found …

Breast and thyroid cancers are two malignancies with highest incidence in women. These
cancers often occur metachronously. Women with thyroid cancer are at increased risk for …

Calcitriol, the hormonally active form of vitamin D, exerts multiple anti-proliferative and pro-
differentiating actions including cell cycle arrest and induction of apoptosis in many …

The endocrine system participates in regulating macrophage maturation, although little is
known about the modulating role of the thyroid hormones. In vitro results demonstrate a …

Nuclear receptors (NRs) are a superfamily of ligand-activated transcription factors that act as
biological sensors and use a combination of mechanisms to modulate positively and …

Acting at a cell surface receptor on the extracellular domain of integrin αvβ3, thyroid
hormone analogues regulate downstream the expression of a large panel of genes relevant …