Identifying progressive gene network perturbation from single-cell RNA-seq data

S Mukherjee, A Carignano, G Seelig… - 2018 40th Annual …, 2018 - ieeexplore.ieee.org
Identifying the gene regulatory networks that control development or disease is one of the
most important problems in biology. Here, we introduce a computational approach, called …

SOMSC: Self-organization-map for high-dimensional single-cell data of cellular states and their transitions

T Peng, Q Nie - bioRxiv, 2017 - biorxiv.org
Measurement of gene expression levels for multiple genes in single cells provides a
powerful approach to study heterogeneity of cell populations and cellular plasticity. While …

Learning and inference with single cell data

S Mukherjee - 2018 - digital.lib.washington.edu
A recent surge in development of high throughput single cell transcriptome sequencing
methods has given rise to single cell data from a variety of cellular contexts. Single cell data …