From bacteria to plants and humans, the glutathione system plays a pleiotropic role in cell
defense against metabolic, oxidative and metal stresses. Glutathione (GSH), the γ-L …

Glyoxalase 2 is a mitochondrial and cytoplasmic protein belonging to the metallo-β-
lactamase family encoded by the hydroxyacylglutathione hydrolase (HAGH) gene. This …

Methylglyoxal (MGO) is an active metabolite of glucose and plays a prominent role in the
pathogenesis of diabetic vascular complications, including endothelial cell apoptosis …

Nanoplastics (NPs) are defined as a group of emerging pollutants. However, the adverse
effect of NPs and/or heavy metals on mammals is still largely unclear. Therefore, we …

Diabetic retinopathy (DR) is a major cause of blindness in adult, and the accumulation of
advanced glycation end products (AGEs) is a major pathologic event in DR. Methylglyoxal …

Key message Elevated methylglyoxal levels contribute to ammonium-induced growth
disorders in Arabidopsis thaliana. Methylglyoxal detoxification pathway limitation, mainly the …

Traumatic stress may chronically affect master homeostatic systems at the crossroads of
peripheral and central susceptibility pathways and lead to the biological embedment of …

Significance: Redox pioneer Helmut Sies attempted to explain reactive species' challenges
faced by organelles, cells, tissues, and organs via three complementary definitions:(i) …

Spinal cord ischemia-reperfusion (IR) injury (SCIRI) is a significant secondary injury that
causes damage to spinal cord neurons, leading to the impairment of spinal cord sensory …

Lentil is an important pulses crop but it's short stature and slow growth rate make it
vulnerable to weed competition, limiting crop productivity. There is need to identify herbicide …