Acquired Immunodeficiency Syndrome (AIDS) is a human viral infectious disease caused by
the positive-sense single-stranded (ss) RNA Human Immunodeficiency Virus …

Human immunodeficiency virus (HIV) is the etiological agent of acquired immunodeficiency
syndrome (AIDS). Nowadays, FDA has approved over thirty antiretroviral drugs grouped in …

Currently, HIV-1 non-nucleoside reverse transcriptase inhibitors (NNRTIs) are a major
component of the highly active anti-retroviral therapy (HAART) regimen. However, the …

The development of metabolic derangements as a result of HIV treatment has been an
important area of research since the introduction of zidovudine in the 1980's. Antiretroviral …

Real-life use of Doravirine in treatment-experienced people... : Medicine Real-life use of
Doravirine in treatment-experienced people living with HIV: A multicenter Italian study : Medicine …

Background: Few data are available about the efficacy, durability, and tolerability of
doravirine (DOR)+ integrase strand inhibitors (INI) as a switching strategy among …

Objectives Doravirine shows a rather distinct resistance profile within the nonnucleoside
reverse transcriptase inhibitor (NNRTI) class. This study aimed to evaluate the phenotypic …

In the last three decades, there has been a considerable improvement in human
immunodeficiency virus (HIV) therapy. Acquired immunodeficiency syndrome (AIDS) is no …

To further investigate and explore the new luminescent materials, three new salts with
triazole-based skeletons, namely,[HCNT]+ X−(X= BS (1), PS (2) and SS∙ H 2 O (3))[CNT= 4 …

Here, we reported a novel series of “dual-site” binding diarylpyrimidine (DAPY) derivatives
targeting both the NNRTI adjacent site and NNRTIs binding pocket (NNIBP). The anti-HIV-1 …