Rationale Prior reviews have examined how stress, broadly defined, interacts with genetic diathesis in the pathogenesis of internalizing (ie, depressive and anxiety) disorders. Recent …
Objective: To perform a meta-analysis including all relevant studies exploring the interaction. Data Sources: We identified studies published through November 2009 in PubMed. Study …
N Risch, R Herrell, T Lehner, KY Liang, L Eaves, J Hoh… - Jama, 2009 - jamanetwork.com
Context Substantial resources are being devoted to identify candidate genes for complex mental and behavioral disorders through inclusion of environmental exposures following the …
WW Eaton, H Shao, G Nestadt, BH Lee… - Archives of general …, 2008 - jamanetwork.com
Context There are no studies of the natural history of major depressive disorder that lack prevalence and clinic biases. Objectives To estimate risk factors for first lifetime onset and …
EE Werner - Handbook of resilience in children, 2012 - Springer
Since the mid-1980s, a number of investigators from different disciplines—child development, pediatrics, psychology, psychiatry, and sociology—have focused on the …
An updated review of 34 human observational studies indicates that the length polymorphism of the serotonin transporter gene moderates the effect of environmental …
Adversity in childhood has effects on mental and physical health, not only in childhood but across the lifespan. A chief task of our research has been to define the pathways by which …
In the three years since the most recent meta-analysis of the association between the serotonin transported promoter polymorphism (5-HTTLPR), stress and the development of …
Y Ding, J Dai - Depressive Disorders: Mechanisms, Measurement and …, 2019 - Springer
Stress is an adaptive response to environment aversive stimuli and a common life experience of one's daily life. Chronic or excessive stress especially that happened in early …