Multiple organ dysfunction in SARS-CoV-2: MODS-CoV-2

C Robba, D Battaglini, P Pelosi… - Expert review of …, 2020 - Taylor & Francis
In December 2019, an outbreak of viral pneumonia caused by a novel coronavirus (since
named SARS-CoV-2) was identified in Wuhan, China. Within few months, this disease–now …

Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies

M Lopes-Pacheco, PL Silva, FF Cruz… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory disease coronavirus 2 (SARS-CoV-2, formerly 2019-nCoV) is a
novel coronavirus that has rapidly disseminated worldwide, causing the coronavirus disease …

The inflammasome in times of COVID-19

JC de Rivero Vaccari, WD Dietrich, RW Keane… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses (CoVs) are members of the genus Betacoronavirus and the Coronaviridiae
family responsible for infections such as severe acute respiratory syndrome (SARS), Middle …

Chest physiotherapy: An important adjuvant in critically ill mechanically ventilated patients with COVID-19

D Battaglini, C Robba, S Caiffa, L Ball, I Brunetti… - Respiratory physiology …, 2020 - Elsevier
In late 2019, an outbreak of a novel human coronavirus causing respiratory disease was
identified in Wuhan, China. The virus spread rapidly worldwide, reaching pandemic status …

[HTML][HTML] Noninvasive respiratory support and patient self-inflicted lung injury in COVID-19: a narrative review

D Battaglini, C Robba, L Ball, PL Silva, FF Cruz… - British Journal of …, 2021 - Elsevier
COVID-19 pneumonia is associated with hypoxaemic respiratory failure, ranging from mild
to severe. Because of the worldwide shortage of ICU beds, a relatively high number of …

Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

Ten things you need to know about intensive care unit management of mechanically ventilated patients with COVID-19

C Robba, D Battaglini, L Ball, P Pelosi… - Expert Review of …, 2021 - Taylor & Francis
Introduction: The ongoing pandemic caused by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2) has posed important challenges for clinicians and health-care …

Coronavirus disease 2019 phenotypes, lung ultrasound, chest computed tomography and clinical features in critically ill mechanically ventilated patients

D Orlandi, D Battaglini, C Robba, M Vigano… - Ultrasound in Medicine …, 2021 - Elsevier
Chest computed tomography (CT) may provide insights into the pathophysiology of
coronavirus disease 2019 (COVID-19), although it is not suitable for a timely bedside …

Failed clinical trials on COVID-19 acute respiratory distress syndrome in hospitalized patients: common oversights and streamlining the development of clinically …

D Battaglini, F Cruz, C Robba, P Pelosi… - Expert Opinion on …, 2022 - Taylor & Francis
Introduction The coronavirus disease 2019 (COVID-19) pandemic has put a strain on global
healthcare systems. Despite admirable efforts to develop rapidly new pharmacotherapies …

An update on the pharmacological management of acute respiratory distress syndrome

D Battaglini, IG Iavarone… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Acute respiratory distress syndrome (ARDS) is characterized by acute
inflammatory injury to the lungs, alterations in vascular permeability, loss of aerated tissue …