A role for an HTLV-1 vaccine?

L Ratner - Frontiers in immunology, 2022 - frontiersin.org
HTLV-1 is a global infection with 5-20 million infected individuals. Although only a minority of
infected individuals develop myelopathy, lymphoproliferative malignancy, or inflammatory …

A platform technology for generating subunit vaccines against diverse viral pathogens

A Young, A Isaacs, CAP Scott, N Modhiran… - Frontiers in …, 2022 - frontiersin.org
The COVID-19 pandemic response has shown how vaccine platform technologies can be
used to rapidly and effectively counteract a novel emerging infectious disease. The speed of …

Novel insights into human T‐lymphotropic virus type‐1 (HTLV‐1) pathogenesis‐host interactions in the manifestation of HTLV‐1‐associated myelopathy/tropical …

S Ahmadi Ghezeldasht, A Mosavat… - Reviews in Medical …, 2024 - Wiley Online Library
Human T‐lymphotropic virus type‐1 (HTLV‐1) was the first discovered human oncogenic
retrovirus, the etiological agent of two serious diseases have been identified as adult T‐cell …

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

JS O'Donnell, A Isaacs, V Jakob, C Lebas… - Frontiers in …, 2022 - frontiersin.org
Various chemical adjuvants are available to augment immune responses to non-replicative,
subunit vaccines. Optimized adjuvant selection can ensure that vaccine-induced immune …

A single immunization with H5N1 virus-like particle vaccine protects chickens against divergent H5N1 influenza viruses and vaccine efficacy is determined by adjuvant …

D Kong, Y He, J Wang, L Chi, X Ao, H Ye… - Emerging Microbes & …, 2024 - Taylor & Francis
The H5N1 subtype highly pathogenic avian influenza virus (HPAIV) reveals high variability
and threatens poultry production and public health. To prevent the spread of H5N1 HPAIV …

Protein nanoparticle-mediated delivery of recombinant influenza hemagglutinin enhances immunogenicity and breadth of the antibody response

AJ Badten, A Ramirez… - ACS Infectious …, 2023 - ACS Publications
The vast majority of seasonal influenza vaccines administered each year are derived from
virus propagated in eggs using technology that has changed little since the 1930s. The …

Design and Evolution of Enhanced Peptide–Peptide Ligation for Modular Transglutaminase Assembly

AH Keeble, DP Wood, M Howarth - Bioconjugate Chemistry, 2023 - ACS Publications
Robust and precise tools are needed to enhance the functionality and resilience of synthetic
nanoarchitectures. Here, we have employed directed evolution and rational design to build …

Democratising large scale instrument-based science through e-Infrastructure

D Abramson, DS Barkauskas, J Carroll… - 2022 IEEE 18th …, 2022 - ieeexplore.ieee.org
Modern scientific instruments are becoming essential for discoveries because they provide
unprecedented insight into physical or biological events–often in real time. However, these …

Concerns regarding vaccination as a management strategy against koala retrovirus

BA Joyce, D Watterson, A Isaacs, KJ Chappell - bioRxiv, 2021 - biorxiv.org
Koalas are of great cultural, ecological and economic significance to Australia. However,
they are in steep decline throughout much of their geographic range, with the recently …

[引用][C] Structure-guided vaccine and therapeutic design for emerging viruses

C Scott - 2023 - espace.library.uq.edu.au
The need for rapid response vaccines and therapeutics to counter emerging viral diseases
has been highlighted by the ongoing COVID-19 pandemic. The University of Queensland …