Iron is a trace metal element necessary to maintain life and is also involved in a variety of
biological processes. Aging refers to the natural life process in which the physiological …

There are multiple diseases or conditions such as hereditary hemochromatosis, hemophilia,
thalassemia, sickle cell disease, aging, and estrogen deficiency that can cause iron …

Ferroptosis is an iron‐dependent cell death that has been found to aggravate the
progression of osteoarthritis (OA) and gut microbiota‐OA axis refers to the bidirectional …

Recent data on the distribution and influence of copper, zinc and cadmium in glial cells are
summarized. This review also examines the relationship between those metals and their …

The process of cellular senescence is rapidly emerging as a modulator of organismal aging
and disease. Targeting the development and removal of senescent cells is considered a …

Recent advances in understanding the role of mitochondrial dysfunction in
neurodegenerative diseases have expanded the opportunities for neurotherapeutics …

Abstract Context Schisandrin B (Sch B), an active ingredient from Schisandrae chinensis
(Turcz.) Baill.(Schisandraceae) Fructus, possesses diverse pharmacological activities …

Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND)
comprise a group of illnesses marked by memory and behavioral dysfunction that can occur …

Background Epigenetic clocks constructed from DNA methylation patterns have emerged as
excellent predictors of aging and aging-related health outcomes. Iron, a crucial element, is …

Iron plays a crucial role in many physiological processes, including oxygen transport,
bioenergetics, and immune function. Iron is assimilated from food and also recycled from …