Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Y Xiong, Y Liu, L Cao, D Wang, M Guo… - Emerging microbes & …, 2020 - Taylor & Francis
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak
has caused devastating mortality and posed a great threat to public health. However, efforts …

First case of COVID-19 complicated with fulminant myocarditis: a case report and insights

JH Zeng, YX Liu, J Yuan, FX Wang, WB Wu, JX Li… - Infection, 2020 - Springer
Abstract Background Coronavirus disease 2019 (COVID-19) has been demonstrated to be
the cause of pneumonia. Nevertheless, it has not been reported as the cause of acute …

Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position paper

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Identification of a potential mechanism of acute kidney injury during the COVID-19 outbreak: a study based on single-cell transcriptome analysis

X Pan, D Xu, H Zhang, W Zhou, L Wang, X Cui - Intensive care medicine, 2020 - Springer
Dear Editor, Tens of thousands of humans were infected with severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) within a short period of time, and the infection …

Neurological involvement in COVID-19 and potential mechanisms: a review

G Aghagoli, B Gallo Marin, NJ Katchur, F Chaves-Sell… - Neurocritical care, 2021 - Springer
As the current understanding of COVID-19 continues to evolve, a synthesis of the literature
on the neurological impact of this novel virus may help inform clinical management and …

Reduction and functional exhaustion of T cells in patients with coronavirus disease 2019 (COVID-19)

B Diao, C Wang, Y Tan, X Chen, Y Liu, L Ning… - Frontiers in …, 2020 - frontiersin.org
Background: The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has posed great threat to human health …

Clinical and high-resolution CT features of the COVID-19 infection: comparison of the initial and follow-up changes

Y Xiong, D Sun, Y Liu, Y Fan, L Zhao, X Li… - Investigative …, 2020 - journals.lww.com
Objectives In late December 2019, an outbreak of coronavirus disease (COVID-19) in
Wuhan, China was caused by a novel coronavirus, newly named severe acute respiratory …

Cytokine storm—definition, causes, and implications

D Jarczak, A Nierhaus - International journal of molecular sciences, 2022 - mdpi.com
The human innate and adaptive immune systems consist of effector cells producing
cytokines (interleukins, interferons, chemokines, and numerous other mediators). Usually, a …

Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice

FS Oladunni, JG Park, PA Pino, O Gonzalez… - Nature …, 2020 - nature.com
Vaccine and antiviral development against SARS-CoV-2 infection or COVID-19 disease
would benefit from validated small animal models. Here, we show that transgenic mice …

Overlapping and discrete aspects of the pathology and pathogenesis of the emerging human pathogenic coronaviruses SARS‐CoV, MERS‐CoV, and 2019‐nCoV

J Liu, X Zheng, Q Tong, W Li, B Wang… - Journal of medical …, 2020 - Wiley Online Library
Abstract First reported from Wuhan, The People's Republic of China, on 31 December 2019,
the ongoing outbreak of a novel coronavirus (2019‐nCoV) causes great global concerns …