Analysis of 92 deceased patients with COVID‐19
F Yang, S Shi, J Zhu, J Shi, K Dai… - Journal of medical …, 2020 - Wiley Online Library
This retrospective study aimed to analyze the clinical characteristics and complications in
death cases with novel coronavirus disease‐19 (COVID‐19). We collected the medical …
death cases with novel coronavirus disease‐19 (COVID‐19). We collected the medical …
Clinical and laboratory predictors of in-hospital mortality in patients with coronavirus disease-2019: a cohort study in Wuhan, China
K Wang, P Zuo, Y Liu, M Zhang, X Zhao… - Clinical infectious …, 2020 - academic.oup.com
Background This study aimed to develop mortality-prediction models for patients with
coronavirus disease-2019 (COVID-19). Methods The training cohort included consecutive …
coronavirus disease-2019 (COVID-19). Methods The training cohort included consecutive …
[HTML][HTML] Pathogenic human coronavirus infections: causes and consequences of cytokine storm and immunopathology
R Channappanavar, S Perlman - Seminars in immunopathology, 2017 - Springer
Human coronaviruses (hCoVs) can be divided into low pathogenic and highly pathogenic
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …
coronaviruses. The low pathogenic CoVs infect the upper respiratory tract and cause mild …
[HTML][HTML] Longitudinal changes of inflammatory parameters and their correlation with disease severity and outcomes in patients with COVID-19 from Wuhan, China
Abstract Background Coronavirus disease 2019 (COVID-19) is a newly emerging infectious
disease and rapidly escalating epidemic caused by the severe acute respiratory syndrome …
disease and rapidly escalating epidemic caused by the severe acute respiratory syndrome …
Inhibition of Bruton tyrosine kinase in patients with severe COVID-19
M Roschewski, MS Lionakis, JP Sharman… - Science …, 2020 - science.org
Patients with severe COVID-19 have a hyperinflammatory immune response suggestive of
macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage signaling and …
macrophage activation. Bruton tyrosine kinase (BTK) regulates macrophage signaling and …
[HTML][HTML] Psycho-neuroendocrine-immune interactions in COVID-19: potential impacts on mental health
Coronavirus disease 2019 (COVID-19) is caused by the Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
Syndrome Coronavirus 2 (SARS-CoV-2). The impacts of the disease may be beyond the …
Weathering the COVID-19 storm: lessons from hematologic cytokine syndromes
A subset of patients with severe COVID-19 develop profound inflammation and multi-organ
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …
dysfunction consistent with a “Cytokine Storm Syndrome”(CSS). In this review we compare …
[HTML][HTML] Different innate and adaptive immune responses to SARS-CoV-2 infection of asymptomatic, mild, and severe cases
R Carsetti, S Zaffina, E Piano Mortari, S Terreri… - Frontiers in …, 2020 - frontiersin.org
SARS-CoV-2 is a novel coronavirus, not encountered before by humans. The wide spectrum
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
of clinical expression of SARS-CoV-2 illness suggests that individual immune responses to …
[HTML][HTML] Animal models for COVID-19: hamsters, mouse, ferret, mink, tree shrew, and non-human primates
S Shou, M Liu, Y Yang, N Kang, Y Song… - Frontiers in …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus
causing acute respiratory tract infection in humans. The virus has the characteristics of rapid …
causing acute respiratory tract infection in humans. The virus has the characteristics of rapid …
[HTML][HTML] Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity
CD Heer, DJ Sanderson, LS Voth… - Journal of Biological …, 2020 - ASBMB
Poly (ADP-ribose) polymerase (PARP) superfamily members covalently link either a single
ADP-ribose (ADPR) or a chain of ADPR units to proteins using NAD as the source of ADPR …
ADP-ribose (ADPR) or a chain of ADPR units to proteins using NAD as the source of ADPR …