Kidney stones (also known as urinary stones or nephrolithiasis) are highly prevalent,
affecting approximately 10% of adults worldwide, and the incidence of stone disease is …

Genome-wide association studies (GWAS) have identified thousands of genetic variants
linked to the risk of human disease. However, GWAS have so far remained largely …

Background Mounting evidence indicates that the gut microbiome (GMB) plays an essential
role in kidney stone (KS) formation. In this study, we conducted a systematic review and …

Biomineralization is a normal physiological process that includes nucleation, crystal growth,
phase transformation, and orientation evolution. Notably, artificially induced …

Kidney stone disease causes significant morbidity and increases health care utilization. In
this work, we decipher the cellular and molecular niche of the human renal papilla in …

Kidney stone disease (KSD) is a complex disorder with high heritability and prevalence. We
performed a large genome-wide association study (GWAS) meta-analysis for KSD to date …

When the filtrate of the glomerulus flows through the renal tubular system, various
microscopic sediment particles, including mineral crystals, are generated. Dislodging these …

Background Kidney stone disease (KSD) is a common condition that affects 10% population
in the United States (US). The relationship between thiamine and riboflavin intake and KSD …

Nephrolithiasis is highly prevalent and brings health and economic burdens to patients. The
augmentation of nephrolithiasis may be associated with exposure to phthalate metabolites …

Purpose: To investigate the relationship between the Oxidative Balance Score (OBS) and
kidney stone risk using NHANES 2007-2018 data, and to explore potential mechanisms and …