The increasing life expectancy of humans has led to a growing numbers of patients with
chronic diseases and end-stage organ failure. Transplantation is an effective approach for …

The shortage of organs and cells from deceased individuals continues to restrict
allotransplantation. Pigs could provide an alternative source of tissue and cells but the …

There is a critical shortage in the number of deceased human organs that become available
for the purposes of clinical transplantation. This problem might be resolved by the …

To diminish the learning curve associated with using swine as models, Swine in the
Laboratory: Surgery, Anesthesia, Imaging, and Experimental Techniques, Second Edition …

Cross-species transplantation (xenotransplantation) offers the prospect of an unlimited
supply of organs and cells for clinical transplantation, thus resolving the critical shortage of …

The immunologic barriers to successful xenotransplantation are related to the presence of
natural anti‐pig antibodies in humans and non‐human primates that bind to antigens …

The limited availability of deceased human organs and cells for the purposes of clinical
transplantation remains critical worldwide. Despite the increasing utilization of 'high …

Preclinical trials of pig-to-nonhuman primate liver xenotransplantation have recently
achieved longer survival times. However, life-threatening thrombocytopenia and coagulation …

The first comprehensive single-source reference on the minipig, this accessible manual
provides a resource for research scientists on the potential and use of the minipig as a …

Several groups have reported extended survival of genetically engineered pig organs in
nonhuman primates, varying from almost 10 months for life-supporting kidney grafts and …