[HTML][HTML] Autophagy related DNA methylation signature predict clinical prognosis and immune microenvironment in low-grade glioma

Q Qiao, Y Wang, R Zhang, Q Pang - Translational Cancer …, 2022 - ncbi.nlm.nih.gov
Background Low-grade glioma (LGG) is a common malignant tumor of the central nervous
system. The clinical prognosis of different patients varies greatly, so exploring appropriate …

[HTML][HTML] Development and validation of a nomogram with an epigenetic signature for predicting survival in patients with lung adenocarcinoma

J Wang, L He, Y Tang, D Li, Y Yang, Z Zeng - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Epigenetic factors play crucial roles in carcinogenesis by modifying chromatin architecture.
Here, we established an epigenetic biosignature-based model for examining survival in …

GrimAge is elevated in older adults with mild COVID-19 an exploratory analysis

P García-delaTorre, NA Rivero-Segura… - GeroScience, 2024 - Springer
COVID-19 has been contained; however, the side effects associated with its infection
continue to be a challenge for public health, particularly for older adults. On the other hand …

Targeting histone deacetylases in head and neck squamous cell carcinoma: molecular mechanisms and therapeutic targets

M Xu, Y Hou, N Li, W Yu, L Chen - Journal of Translational Medicine, 2024 - Springer
The onerous health and economic burden associated with head and neck squamous cell
carcinoma (HNSCC) is a global predicament. Despite the advent of novel surgical …

Multi-omics data analysis reveals the complex roles of age in differentiated thyroid cancer

Y Zhang, Q Chen, L Niu, H Huang, Z Yang, T Liao… - Heliyon, 2024 - cell.com
Aims Age is a major risk factor for differentiated thyroid cancer (DTC); however, the
mechanisms underlying aging-regulated progression of DTC remains unclear. Methods …

Obesity-associated differentially methylated regions in colon cancer

JJ Milner, ZF Chen, J Grayson, SYPK Shiao - Journal of Personalized …, 2022 - mdpi.com
Obesity with adiposity is a common disorder in modern days, influenced by environmental
factors such as eating and lifestyle habits and affecting the epigenetics of adipose-based …

Oncogenic RAS-Pathway Activation Drives Oncofetal Reprogramming and Creates Therapeutic Vulnerabilities in Juvenile Myelomonocytic Leukemia

M Hartmann, M Schoenung, J Rajak, V Maurer, L Hai… - bioRxiv, 2023 - biorxiv.org
Aberrant fetal gene expression facilitates tumor-specific cellular plasticity by hijacking
molecular programs of embryogenesis. Persistent fetal gene signatures in childhood …

Changes in mouse epidermal DNA methylation during development of squamous cell carcinoma in response to UVR

OL Meyer, JD Andersen, C Børsting… - Experimental …, 2024 - Wiley Online Library
Squamous cell carcinoma (SCC) is a common skin cancer, often caused by exposure to
ultraviolet radiation (UVR). Recent studies have shown that changes in DNA methylation …

Elevated EVL Methylation Level in the Normal Colon Mucosa Is a Potential Risk Biomarker for Developing Recurrent Adenomas

M Yu, KT Carter, KK Baker, MW Redman, T Wang… - … Biomarkers & Prevention, 2023 - AACR
Background: Individuals with adenomatous colorectal polyps undergo repeated
colonoscopy surveillance to identify and remove metachronous adenomas. However, many …

[引用][C] 环黄芪醇抗衰老药理作用的研究进展

张阳焕, 袁洋, 孙曼婷, 刘静 - 中国细胞生物学学报, 2021