It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis and functional changes, both of which are essential for the initiation and completion of the …
K Curtius, A Dewanji, WD Hazelton, JH Rubenstein… - Cancer research, 2021 - AACR
Cancer screening and early detection efforts have been partially successful in reducing incidence and mortality, but many improvements are needed. Although current medical …
S Chen, K Huang, L Zou, L Chen, P Hu - BMC Pulmonary Medicine, 2023 - Springer
Aim To investigate the diagnostic value of combined detection of SHOX2 and RASSF1A gene methylation with carcinoembryonic antigen (CEA) level in diagnosing malignant …
HF Bode, A Heikkinen, S Lundgren, J Kaprio… - Twin Research and …, 2022 - cambridge.org
DNA methylation-based age acceleration (DNAmAA) is associated with cancer, with both cancer tissue and blood showing increased DNAmAA. We aimed to investigate whether …
A Kuenstner, J Schwarting, H Witte, P Xing, V Bernard… - medRxiv, 2023 - medrxiv.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive malignancy originating from plasmacytoid/common dendritic cells (pDCs/cDCs) with a …
R Jeremian, A Malinowski, Y Lytvyn… - British Journal of …, 2024 - academic.oup.com
This study investigated epigenetic changes, specifically epigenetic ageing, in an adult cohort of healthy individuals using five validated epigenetic clock algorithms and a DNA …
AD Attygalle, JKC Chan, SE Coupland, MQ Du… - Journal of …, 2024 - Springer
The classification of tumors is essential in the diagnosis and clinical management of patients with malignant neoplasms. The World Health Organization (WHO) provides a globally …
1.6 Chromatin alterations and histone modifications 1.7 Noncoding RNA (ncRNA) 1.8 Overview of miRNAs 2. Epigenetic alterations and colorectal polyps and cancer 2.1 …
Background: Hair products may be a source of harmful chemicals and have been linked to age-related health outcomes. We investigated whether the use of hair products is related to …