Conservation of aging and cancer epigenetic signatures across human and mouse

RF Pérez, JR Tejedor… - Molecular biology …, 2021 - academic.oup.com
Aging and cancer are two interrelated processes, with aging being a major risk factor for the
development of cancer. Parallel epigenetic alterations have been described for both …

[HTML][HTML] Potential of melatonin to reverse epigenetic aberrations in oral cancer: new findings

E Gil-Martín, E Ramos, F López-Muñoz, J Egea… - EXCLI …, 2023 - ncbi.nlm.nih.gov
It is now an accepted principle that epigenetic alterations cause cellular dyshomeostasis
and functional changes, both of which are essential for the initiation and completion of the …

Optimal timing for cancer screening and adaptive surveillance using mathematical modeling

K Curtius, A Dewanji, WD Hazelton, JH Rubenstein… - Cancer research, 2021 - AACR
Cancer screening and early detection efforts have been partially successful in reducing
incidence and mortality, but many improvements are needed. Although current medical …

Diagnostic value of SHOX2, RASSF1A gene methylation combined with CEA level detection in malignant pleural effusion

S Chen, K Huang, L Zou, L Chen, P Hu - BMC Pulmonary Medicine, 2023 - Springer
Aim To investigate the diagnostic value of combined detection of SHOX2 and RASSF1A
gene methylation with carcinoembryonic antigen (CEA) level in diagnosing malignant …

Differences in DNA Methylation-Based Age Prediction Within Twin Pairs Discordant for Cancer

HF Bode, A Heikkinen, S Lundgren, J Kaprio… - Twin Research and …, 2022 - cambridge.org
DNA methylation-based age acceleration (DNAmAA) is associated with cancer, with both
cancer tissue and blood showing increased DNAmAA. We aimed to investigate whether …

Genome-wide DNA methylation-analysis delineates blastic plasmacytoid dendritic cell neoplasm from related entities and identifies distinct molecular features

A Kuenstner, J Schwarting, H Witte, P Xing, V Bernard… - medRxiv, 2023 - medrxiv.org
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) constitutes a rare and aggressive
malignancy originating from plasmacytoid/common dendritic cells (pDCs/cDCs) with a …

Skin photoageing following sun exposure is associated with decreased epigenetic and biologic age, and correlates with basal cell carcinoma phenotype

R Jeremian, A Malinowski, Y Lytvyn… - British Journal of …, 2024 - academic.oup.com
This study investigated epigenetic changes, specifically epigenetic ageing, in an adult
cohort of healthy individuals using five validated epigenetic clock algorithms and a DNA …

What is new in the 5th edition of the World Health Organization classification of mature B and T/NK cell tumors and stromal neoplasms?

AD Attygalle, JKC Chan, SE Coupland, MQ Du… - Journal of …, 2024 - Springer
The classification of tumors is essential in the diagnosis and clinical management of patients
with malignant neoplasms. The World Health Organization (WHO) provides a globally …

Epigenetic alterations in the gastrointestinal tract: Current and emerging use for biomarkers of cancer

WM Gradya - Novel Approaches to Colorectal Cancer, 2021 - books.google.com
1.6 Chromatin alterations and histone modifications 1.7 Noncoding RNA (ncRNA) 1.8
Overview of miRNAs 2. Epigenetic alterations and colorectal polyps and cancer 2.1 …

Associations between use of chemical hair products and epigenetic age: Findings from the Sister Study

CJ Chang, KM O'Brien, JK Kresovich… - Environmental …, 2024 - journals.lww.com
Background: Hair products may be a source of harmful chemicals and have been linked to
age-related health outcomes. We investigated whether the use of hair products is related to …